IRF1 wt Allele

Known as: IRF-1, Interferon Regulatory Factor 1 wt Allele, MAR 
Human IRF1 wild-type allele is located within 5q23-q31 and is approximately 9 kb in length. This allele, which encodes interferon regulatory factor 1… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
051019892017

Papers overview

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Highly Cited
2003
Highly Cited
2003
Toll-like receptor 3 (TLR3) belongs to a family of evolutionary conserved innate immune recognition molecules and recognizes… (More)
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Highly Cited
2000
Highly Cited
2000
IL-12 is a cytokine that links innate and adaptive immunity. Its subunit p40 is induced in macrophages following IFN-gamma/LPS… (More)
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Highly Cited
1999
Highly Cited
1999
We investigated the molecular mechanism for the synergistic induction of inducible nitric oxide synthase transcription by TNF… (More)
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1999
1999
The transcription factor IRF-1 has been implicated in tumor suppression: IRF-1 suppresses cell transformation and mediates… (More)
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1998
1998
Histone genes display a peak in transcription in early S phase and are ideal models for cell cycle-regulated gene expression. We… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Interferons (IFNs) are a class of cytokines which confer cellular resistance against viral infections. Type I (IFN… (More)
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1996
1996
The TAP1 and LMP2 genes are central for class I MHC function and share a common promoter. Here, we analyze the molecular… (More)
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Highly Cited
1993
Highly Cited
1993
One of the most frequent cytogenetic abnormalities in human leukemia and myelodysplasia is an interstitial deletion within… (More)
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Highly Cited
1990
Highly Cited
1990
Interferons (IFNs) are a heterogeneous family of cytokines that exhibits multiple biological activities. Upon viral infection… (More)
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Highly Cited
1989
Highly Cited
1989
Nuclear protein IRF-1 (interferon regulatory factor 1) was earlier shown to bind to cis-acting regulatory elements present on… (More)
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