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IRF1 wt Allele

Known as: IRF-1, Interferon Regulatory Factor 1 wt Allele, MAR 
Human IRF1 wild-type allele is located within 5q23-q31 and is approximately 9 kb in length. This allele, which encodes interferon regulatory factor 1… 
National Institutes of Health

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Related topics

9 relations
5q31.1ApoptosisHomo sapiensIRF1 protein, human

Broader (1)

IRF1 gene

Papers overview

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Highly Cited
2009
Highly Cited
2009
Anthocyanins from black soybean seed coats preferentially inhibit TNF-alpha-mediated induction of VCAM-1 over ICAM-1 through the regulation of GATAs and IRF-1.
Adhesion molecules have a key role in pathological inflammation. Thus, we investigated the effect of anthocyanins on the… 
Highly Cited
2004
Highly Cited
2004
A role for casein kinase II phosphorylation in the regulation of IRF-1 transcriptional activity
The Interferon Regulatory Factors (IRFS) play an important role in the transcriptional control of growth regulatory and… 
2004
2004
IFN-gamma enhances TRAIL-induced apoptosis through IRF-1.
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family and a potent inducer of… 
Highly Cited
2003
Highly Cited
2003
IRF-1 reverts the transformed phenotype of oncogenically transformed cells in vitro and in vivo
The expression of the transcriptional activator and tumor suppressor IRF-1 induces multiple effects that counteract the growth of… 
2001
2001
The Cell Cycle Control Element of Histone H4 Gene Transcription Is Maximally Responsive to Interferon Regulatory Factor Pairs IRF-1/IRF-3 and IRF-1/IRF-7*
Interferon regulatory factors (IRFs) are transcriptional mediators of interferon-responsive signaling pathways that are involved… 
1999
1999
Interferon Regulatory Factor 1 Mediates the Interferon-γ Induction of the Human Immunoproteasome Subunit Multicatalytic Endopeptidase Complex-like 1*
Proteasomes generate antigenic peptides from intracellular proteins for presentation to the immune system by the major… 
Highly Cited
1998
Highly Cited
1998
Cell Cycle Regulation of Histone H4 Gene Transcription Requires the Oncogenic Factor IRF-2*
Histone genes display a peak in transcription in early S phase and are ideal models for cell cycle-regulated gene expression. We… 
Highly Cited
1998
Highly Cited
1998
Molecular cloning of a novel interferon regulatory factor in Japanese flounder, Paralichthys olivaceus.
A complementary DNA library was constructed in lambda ZAP II using messenger RNA from the leukocytes of some heterocloned… 
Highly Cited
1996
Highly Cited
1996
Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q- associated leukemias.
The transcription factor IRF-1 (interferon regulatory factor 1) is an activator of type I interferon and interferon-inducible… 
Highly Cited
1989
Highly Cited
1989
Sequence of a cDNA coding for human IRF-1.
We have previously isolated and sequenced a cDNA clone encoding a mouse IFN regulatory factor 1 (IRF-1) (Miyamoto, M., Fujita, T… 
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