G. Stein

Publications918
h-index108
Citations47,365
Highly Influential Citations1,559
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • J. Lian
  • 700 Publications, 43,805 Citations
  • J. Stein
  • 542 Publications, 29,023 Citations
  • A. V. van Wijnen
  • 506 Publications, 27,136 Citations
  • S. K. Zaidi
  • 110 Publications, 5,685 Citations
  • Publications
  • Influence
Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the…
The relationship of cell proliferation to the temporal expression of genes characterizing a developmental sequence associated with bone cell differentiation was examined in primary diploid cultures… Expand
  • 1,437
  • 49
Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression*
Both activating and null mutations of proteins required for canonical WNT signaling have revealed the importance of this pathway for normal skeletal development. However, tissue-specific… Expand
  • 850
  • 47
A microRNA signature for a BMP2-induced osteoblast lineage commitment program
Bone morphogenetic proteins (BMPs) are potent morphogens that activate transcriptional programs for lineage determination. How BMP induction of a phenotype is coordinated with microRNAs (miRNAs) that… Expand
  • 448
  • 37
Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype.
I. Introduction A FUNCTIONAL relationship between cell growth and the initiation and progression of events associated with differentiation has been a fundamental question challenging developmental… Expand
  • 960
  • 31
Self‐renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase
Competency for self‐renewal of human embryonic stem (ES) cells is linked to pluripotency. However, there is a critical paucity of fundamental parameters of human ES cell division. In this study we… Expand
  • 388
  • 28
Relationship of cell growth to the regulation of tissue‐specific gene expression during osteoblast differentiation
The relationship of cell proliferation to the temporal expression of genes characterizing a developmental sequence associated with bone cell differentiation can be examined in primary diploid… Expand
  • 859
  • 25
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors.
Formation of skeletal elements during embryogenesis and the dynamic remodeling of bone in the adult involve an exquisite interplay of developmental cues, signaling proteins, transcription factors,… Expand
  • 421
  • 25
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2
  • Y. Zhang, R. Xie, +4 authors G. Stein
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 31 May 2011
Lineage progression in osteoblasts and chondrocytes is stringently controlled by the cell-fate–determining transcription factor Runx2. In this study, we directly addressed whether microRNAs (miRNAs)… Expand
  • 313
  • 25
  • Open Access
Networks and hubs for the transcriptional control of osteoblastogenesis
We present an overview of the concepts of tissue-specific transcriptional control mechanisms essential for development of the bone cell phenotype. BMP2 induced transcription factors constitute a… Expand
  • 398
  • 23
Osteoblast differentiation and skeletal development are regulated by Mdm2–p53 signaling
Mdm2 is required to negatively regulate p53 activity at the peri-implantation stage of early mouse development. However, the absolute requirement for Mdm2 throughout embryogenesis and in… Expand
  • 231
  • 22