IRF1 protein, human

Known as: Interferon Regulatory Factor 1, IRF-1, interferon regulatory factor 1, human 
Interferon regulatory factor 1 (325 aa, ~37 kDa) is encoded by the human IRF1 gene. This protein plays a role in the regulation of interferon gene… (More)
National Institutes of Health

Papers overview

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2015
2015
Basic leucine zipper transcription factor Batf2 is poorly described, whereas Batf and Batf3 have been shown to play essential… (More)
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2014
2014
Osteopontin (OPN), a secreted phosphoglycoprotein, plays important roles in tumor growth, invasion, and metastasis for many types… (More)
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2008
2008
Interleukin-12 (IL-12) and interferon-γ (IFN-γ) drive T helper type 1 (TH1) differentiation, but the mechanisms underlying the… (More)
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2008
2008
Regulatory T (Treg) cells are critical in inducing and maintaining tolerance. Despite progress in understanding the basis of… (More)
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Highly Cited
2007
Highly Cited
2007
A subgroup of genes induced by IFN-gamma requires both STAT1 and IRF1 for transcriptional activation. Using WT, stat1(-/-), or… (More)
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Highly Cited
2000
Highly Cited
2000
In studying biological roles of interferon regulatory factor (IRF)-1 tumor suppressor in cervical carcinogenesis, we found that… (More)
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Highly Cited
1998
Highly Cited
1998
IFN-gamma induces a number of cellular programs functional in innate and adaptive resistance to infectious pathogens. It has… (More)
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1997
1997
The Epstein-Barr virus (EBV) EBNA1 gene promoter active in the type I program of restricted viral latency was recently identified… (More)
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1995
1995
The Interferon Regulatory Factors-1 and -2 (IRF-1 and IRF-2) play a transcriptional role in the regulation of the IFN-beta gene… (More)
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Highly Cited
1989
Highly Cited
1989
Viral infections commonly induce expression of type I interferon (IFN) genes. The induction is transient and involves… (More)
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