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IRF1 gene

Known as: interferon regulatory factor-1, Interferon Regulatory Factor 1 Gene, MAR 
This gene plays a role in the transcriptional activation of target genes. It is also involved in promoting apoptosis.
National Institutes of Health

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ApoptosisHomo sapiensIRF1 protein, humanInterferon Regulatory Factor 1

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IRF1 wt Allele

Papers overview

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2012
2012
Abstract 2330: Murine interferon-α inhibits aortic endothelial outgrowth
Although Interferon-α exerts anti-angiogenic effects, it has proven clinically useful in only a handful of tumor types. IFNα has… 
2011
2011
Expression Transcription 1 ( STAT 1 )-activated Gene Signal Transducer and Activator of 1-like ( DOT 1 L ) Interaction Is Required for A Novel Disrupter of Telomere Silencing Gene Regulation :
2005
2005
Differentiation-dependent activation of interferon-stimulated gene factors and transcription factor NF-cB in mouse embryonal carcinoma cells ( antiviral state / interferon sensitivity )
We have recently shown that the adenovirus EIA gene products block interferon-a-induced signal transduction and transcription… 
2004
2004
Transcriptional regulation of the 230 kD bullous pemphigoid antigen (BPAG1) gene expression by interferon regulatory factor 1 (IRF1) and interferon regulatory factor 2 (IRF2) in normal human…
2002
2002
IS-10 Determination of the genetic susceptibilities of p53 and interferon regulatory factor-1 polymorphism in cervical carcinogenesis
2001
2001
Virus-mediated Induction of Interferon A Gene Requires Cooperation between Multiple Binding Factors in the Interferon a !
Transcriptional activation of interferon A (IFNA) gene in virus-infected cells is controlled by a 35-nucleotide inducible element…