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IL2RB protein, human

Known as: Intermediate Affinity Interleukin 2 Receptor Subunit Beta, P70-75, IL-2R Subunit Beta 
Interleukin-2 receptor subunit beta (551 aa, ~61 kDa) is encoded by the human IL2RB gene. This protein is involved in signal transduction-mediated by… Expand
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
The neurotrophin receptor p75 can induce apoptosis both in vitro and in vivo. The mechanisms by which p75 induces apoptosis have… Expand
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Highly Cited
1999
Highly Cited
1999
IL-2 is an important growth and survival factor for T lymphocytes but also sensitizes these cells to Fas-mediated activation… Expand
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Highly Cited
1999
Highly Cited
1999
Signaling through the hematopoietic receptors requires activation of receptor-associated Janus (Jak) kinases. For example, Jak1… Expand
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Highly Cited
1999
Highly Cited
1999
CIS is a cytokine-induced SH2-containing protein that was originally cloned as an interleukin (IL)-3-inducible gene. CIS is known… Expand
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Highly Cited
1997
Highly Cited
1997
The interleukin-2 receptor beta chain (IL-2R beta) is expressed on a variety of hematopoietic cell types, including natural… Expand
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Highly Cited
1996
Highly Cited
1996
One of the earliest events induced by interleukin 2 (IL-2) is tyrosine phosphorylation of cellular proteins, including the IL-2… Expand
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Highly Cited
1995
Highly Cited
1995
In mice lacking the interleukin-2 receptor beta chain (IL-2R beta), T cells were shown to be spontaneously activated, resulting… Expand
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Highly Cited
1995
Highly Cited
1995
The high-affinity interleukin 2 (IL-2) receptor (IL-2R) consists of three subunits: the IL-2R alpha, IL-2R beta c, and IL-2R… Expand
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Highly Cited
1993
Highly Cited
1993
The interleukin 2 receptor beta chain (IL-2R beta) is preferentially expressed in natural killer (NK) cells, but is not detected… Expand
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Highly Cited
1989
Highly Cited
1989
The human high-affinity receptor for interleukin 2 (IL-2) has been proposed as being a membrane complex composed of at least two… Expand
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