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IL2RB protein, human

Known as: Intermediate Affinity Interleukin 2 Receptor Subunit Beta, P70-75, IL-2R Subunit Beta 
Interleukin-2 receptor subunit beta (551 aa, ~61 kDa) is encoded by the human IL2RB gene. This protein is involved in signal transduction-mediated by… 
National Institutes of Health

Related topics

Related topics

19 relations
CD122 AntigensCellular ImmunityCytokine Receptor GeneCytokine Signaling Process

Broader (1)

interleukin-2 receptor beta

Papers overview

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Highly Cited
1998
Highly Cited
1998
Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta.
Interleukin-2 (IL-2) induces heterodimerization of the IL-2 receptor beta (IL-2Rbeta) and gammac chains of its receptor and… 
1993
1993
The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation.
Highly Cited
1992
Highly Cited
1992
c-fos gene induction by interleukin 2: identification of the critical cytoplasmic regions within the interleukin 2 receptor beta chain.
Interleukin 2 (IL-2) plays a critical role in the growth and differentiation of lymphoid cells. The IL-2 signal is delivered… 
Highly Cited
1990
Highly Cited
1990
Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated.
1990
1990
Murine interleukin 2 receptor beta chain: dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertion.
The functional, high-affinity interleukin 2 receptor (IL-2R) consists of at least two receptor components, IL-2R alpha (p55) and… 
1990
1990
Interleukin 2 receptor beta chain expressed in an oligodendroglioma line binds interleukin 2 and delivers growth signal.
Interleukin 2 (IL-2) is a potent growth factor for T lymphocytes, playing a crucial role in the immune response. In view of the… 
1990
1990
Affinity purification of human granulocyte macrophage colony-stimulating factor receptor alpha-chain. Demonstration of binding by photoaffinity labeling.
1990
1990
Differential expression of the interleukin 2 receptor beta (p75) chain on human peripheral blood natural killer subsets.
The interleukin-2 receptor (IL-2R) is composed of at least two subunits, the IL-2R alpha (P55, CD25/Tac) and IL-2R beta (p70-75… 
1989
1989
Erythropoietin receptor and interleukin-2 receptor beta chain: a new receptor family.
Highly Cited
1988
Highly Cited
1988
The human interleukin 2 receptor beta chain (p70). Direct identification, partial purification, and patterns of expression on peripheral blood mononuclear cells
IL-2 binds to high- and low-affinity receptors on activated T cells. The high-affinity receptor was hypothesized to consist of… 
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