IL2RB protein, human

Known as: Intermediate Affinity Interleukin 2 Receptor Subunit Beta, P70-75, IL-2R Subunit Beta 
Interleukin-2 receptor subunit beta (551 aa, ~61 kDa) is encoded by the human IL2RB gene. This protein is involved in signal transduction-mediated by… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2018
051019852018

Papers overview

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2014
2014
Type 1 diabetes (T1D) shows ∼40% concordance rate in monozygotic twins (MZ) suggesting a role for environmental factors and/or… (More)
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2007
2007
Common lymphoid progenitors (CLPs) are lymphoid-lineage-committed progenitor cells. However, they maintain a latent myeloid… (More)
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Highly Cited
1999
Highly Cited
1999
IL-2 is an important growth and survival factor for T lymphocytes but also sensitizes these cells to Fas-mediated activation… (More)
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1999
1999
Signaling through the hematopoietic receptors requires activation of receptor-associated Janus (Jak) kinases. For example, Jak1… (More)
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1998
1998
Interleukin-2 (IL-2) induces heterodimerization of the IL-2 receptor beta (IL-2Rbeta) and gammac chains of its receptor and… (More)
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Highly Cited
1996
Highly Cited
1996
One of the earliest events induced by interleukin 2 (IL-2) is tyrosine phosphorylation of cellular proteins, including the IL-2… (More)
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1995
1995
The high-affinity interleukin 2 (IL-2) receptor (IL-2R) consists of three subunits: the IL-2R alpha, IL-2R beta c, and IL-2R… (More)
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1995
1995
To explore the possible involvement of STAT factors ("signal transducers and activators of transcription") in the interleukin 2… (More)
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Highly Cited
1994
Highly Cited
1994
Interleukin-2 (IL-2) signaling requires the dimerization of the IL-2 receptor beta.(IL-2R beta) and common gamma (gamma c) chains… (More)
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Highly Cited
1993
Highly Cited
1993
The interleukin 2 receptor beta chain (IL-2R beta) is preferentially expressed in natural killer (NK) cells, but is not detected… (More)
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