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interleukin-2 receptor beta

Known as: IL 2 15 Receptor beta, Interleukin-2, 15 Receptor beta Subunit, IL 2Rbeta2 
A receptor subunit that is a shared component of the INTERLEUKIN 2 RECEPTOR and the INTERLEUKIN-15 RECEPTOR. High affinity receptor complexes are… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

CD122 Antigens

Narrower (2)

IL2RB protein, humanIl2rb protein, mouse
IL2RB wt AlleleIn BloodProcess of secretionagonists

Papers overview

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Highly Cited
2003
Highly Cited
2003
Sphingosine 1-Phosphate and Platelet-derived Growth Factor (PDGF) Act via PDGFβ Receptor-Sphingosine 1-Phosphate Receptor Complexes in Airway Smooth Muscle Cells*
Platelet-derived growth factor (PDGF) and sphingosine 1-phosphate (S1P) act via PDGFβ receptor-S1P1 receptor complexes in airway… 
2000
2000
An evaluation of interleukin genes fails to identify clear susceptibility loci for multiple sclerosis
1998
1998
Lymphokine regulation of activation-induced apoptosis in T cells of IL-2 and IL-2R beta knockout mice.
Recent studies using IL-2R alpha knockout mice have generated conflicting results regarding the hypothesis that IL-2/IL-2R… 
1997
1997
Interleukin-15 signals T84 colonic epithelial cells in the absence of the interleukin-2 receptor beta-chain.
Interleukin-15 (IL-15) shares many biological functions with interleukin-2 (IL-2) due to common receptor components. IL-15 binds… 
1995
1995
Supportive cellular elements for hepatic T cell differentiation: T cells expressing intermediate levels of the T cell receptor are cytotoxic against syngeneic hepatoma, and are lost after hepatocyte…
Extrathymic T cells exist in the liver and are often seen in close contact with Kupffer cells in the hepatic sinusoids. Since… 
Highly Cited
1992
Highly Cited
1992
c-fos gene induction by interleukin 2: identification of the critical cytoplasmic regions within the interleukin 2 receptor beta chain.
Interleukin 2 (IL-2) plays a critical role in the growth and differentiation of lymphoid cells. The IL-2 signal is delivered… 
Highly Cited
1991
Highly Cited
1991
Mechanistic studies of transforming growth factor-beta inhibition of IL-2-dependent activation of CD3- large granular lymphocyte functions. Regulation of IL-2R beta (p75) signal transduction.
CD3- large granular lymphocyte (LGL) express constitutive levels of functional IL-2R beta. TGF-beta inhibited several IL-2R beta… 
1990
1990
Murine interleukin 2 receptor beta chain: dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertion.
The functional, high-affinity interleukin 2 receptor (IL-2R) consists of at least two receptor components, IL-2R alpha (p55) and… 
1989
1989
Expression of interleukin-2 receptor beta subunit in hematopoietic malignancies.
The expression of the interleukin-2 (IL-2) receptor was studied in neoplastic cells derived from acute leukemias, T-cell… 
Highly Cited
1988
Highly Cited
1988
The human interleukin 2 receptor beta chain (p70). Direct identification, partial purification, and patterns of expression on peripheral blood mononuclear cells
IL-2 binds to high- and low-affinity receptors on activated T cells. The high-affinity receptor was hypothesized to consist of… 
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