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IL2RB wt Allele

Known as: Interleukin 2 Receptor, Beta wt Allele, Interleukin 15 Receptor, Beta Gene, CD122 
Human IL2RB wild-type allele is located in the vicinity of 22q13.1 and is approximately 24 kb in length. This allele, which encodes interleukin-2… 
National Institutes of Health

Related topics

Related topics

12 relations
22q13.1CD122 AntigensCellular ImmunityCytokine Signaling Process

Broader (1)

IL2RB gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Clinical trial of a humanized anti‐IL‐2/IL‐15 receptor β chain in HAM/TSP
Human T cell lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive… 
2018
2018
CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection
Interrupting T cell costimulatory signals as a strategy to control undesired immune responses, such as occur in autoimmunity or… 
2011
2011
CD8+ CD122+ PD-1- Effektorzellen haben einen wichtigen Einfluss auf die Progression des Typ 1 Diabetes in der NOD Maus
2009
2009
Human CD8 1 CXCR3 1 T cells have the same function as murine CD8 1 CD122 1 Treg
Highly Cited
2005
Highly Cited
2005
Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells.
The nonobese diabetic/severe combined immune deficiency (NOD/SCID) xenotransplantation model has emerged as a widely used assay… 
2003
2003
Activation via the CD 3 and CD 16 Pathway Mediates Interleukin-2-Dependent Autocrine Proliferation of Granular Lymphocytes in Patients With Granular Lymphocyte
Granular lymphocytes (GLs) in patients with GL-proliferative disorders (GLPDs) are known to express the interleukin-2 receptor… 
1991
1991
Interleukin‐4 regulates the interleukin‐2 receptors on human peripheral blood B lymphocytes
The high‐affinity interleukin‐2 (IL‐2) receptor (IL‐2R) consists of the non‐covalent association of at least two subunits, p55… 
1990
1990
Murine interleukin 2 receptor beta chain: dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertion.
The functional, high-affinity interleukin 2 receptor (IL-2R) consists of at least two receptor components, IL-2R alpha (p55) and… 
Highly Cited
1989
Highly Cited
1989
IL-2 regulation of tyrosine kinase activity is mediated through the p70-75 beta-subunit of the IL-2 receptor.
The stimulation of activated human T lymphocytes with IL-2 results in increased tyrosine kinase activity. IL-2 treatment of Tac… 
1989
1989
Two-dimensional analysis of interleukin 2-regulated tyrosine kinase activation mediated by the p70-75 beta subunit of the interleukin 2 receptor.
The proliferation of activated T lymphocytes is dependent on the interaction of the polypeptide growth factor interleukin 2 (IL 2… 
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