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IL2RB gene

Known as: CD122 ANTIGEN, interleukin 2 receptor subunit beta, INTERLEUKIN 2 RECEPTOR, BETA 
This gene is involved in the regulation of myeloid cell development.
National Institutes of Health

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CD122 AntigensCellular ImmunityCytokine Signaling ProcessIL2RB protein, human

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IL2RB wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
IL2RB maintains immune harmony
Autosomal recessive mutations in IL2RB shape immunity and peripheral immune tolerance. 
2018
2018
CD122 blockade restores immunological tolerance in autoimmune type 1 diabetes via multiple mechanisms.
Signaling through IL-2/IL-15Rβ (CD122) is essential for the differentiation and function of T cells and NK cells. A mAb against… 
2018
2018
LCK as a Potential Therapeutic Target for Acute Rejection after Kidney Transplantation: A Bioinformatics Clue
Objectives We aim to identify the key biomarker of acute rejection (AR) after kidney transplantation via bioinformatics methods… 
2017
2017
Intrauterine growth restriction and placental gene expression in severe preeclampsia, comparing early-onset and late-onset forms
Abstract Objective: To evaluate placental gene expression in severe early- or late-onset preeclampsia with intrauterine growth… 
2014
2014
Association of IL-2RA and IL-2RB genes with erosive status in early rheumatoid arthritis patients (ESPOIR and RMP cohorts).
2012
2012
Multistage Analysis of Variants in the Inflammation Pathway and Lung Cancer Risk in Smokers
Background: Tobacco-induced lung cancer is characterized by a deregulated inflammatory microenvironment. Variants in multiple… 
2011
2011
Impact of IL2 and IL2RB genetic polymorphisms in kidney transplantation.
2005
2005
Loss of heterozygosity on chromosome 22q in gastrointestinal stromal tumors (GISTs): a study on 50 cases
Mutational activation of KIT or PDGFRA is considered an early step in pathogenesis of gastrointestinal stromal tumors (GISTs… 
1997
1997
No evidence for a schizophrenia susceptibility gene in the vicinity of IL2RB on chromosome 22.
Pulver et al. [1994a] reported modest linkage evidence for a dominantly (D) inherited "schizophrenia gene" in the vicinity of… 
Highly Cited
1994
Highly Cited
1994
Search for a schizophrenia susceptibility locus on human chromosome 22.
We used 10 highly informative DNA polymorphic markers and genetic linkage analysis to examine whether a gene locus predisposing… 
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