IFIH1 gene

Known as: INTERFERON-INDUCED HELICASE C DOMAIN-CONTAINING PROTEIN 1, Hlcd, Interferon Induced With Helicase C Domain 1 Gene 
This gene is involved in binding to viral ribonucleic acids.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
The type I interferon system is integral to human antiviral immunity. However, inappropriate stimulation or defective negative… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Systemic lupus erythematosus (SLE) is a complex trait characterised by the production of a range of auto-antibodies and a diverse… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2010
Highly Cited
2010
OBJECTIVES Various autoantibodies are detected in the sera of PM/DM patients. Some of them are specific to PM/DM patients and… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Genome-wide association studies (GWASs) are regularly used to map genomic regions contributing to common human diseases, but they… (More)
  • table 1
  • table 2
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The ribonucleic acid (RNA) helicases retinoic acid-inducible gene-I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Genome-wide association (GWA) studies revealed a number of single nucleotide polymorphisms (SNPs) significantly associated with… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
In this study we report convincing statistical support for a sixth type 1 diabetes (T1D) locus in the innate immunity viral RNA… (More)
  • table 4
  • table 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The innate immune system senses viral infection by recognizing a variety of viral components (including double-stranded (ds)RNA… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
IFN-beta promoter stimulator (IPS)-1 was recently identified as an adapter for retinoic acid-inducible gene I (RIG-I) and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Antiviral immunity against a pathogen is mounted upon recognition by the host of virally associated structures. One of these… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?