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ATP Hydrolysis
ATP Hydrolysis is the cleavage of a high-energy phosphate bond of adenosine triphosphate by the addition of water. The energy derived from hydrolysis…
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National Institutes of Health
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50 relations
26S Protease Regulatory Subunit 7, human
ABCB11 gene
ABCB11 protein, human
ATAD5 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Correlation between Steady-state ATP Hydrolysis and Vanadate-induced ADP Trapping in Human P-glycoprotein
K. Kerr
,
Z. Sauna
,
S. Ambudkar
Journal of Biological Chemistry
2001
Corpus ID: 32525909
P-glycoprotein (Pgp) is a transmembrane protein conferring multidrug resistance to cells by extruding a variety of amphipathic…
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Highly Cited
1999
Highly Cited
1999
Both ATP sites of human P-glycoprotein are essential but not symmetric.
C. Hrycyna
,
M. Ramachandra
,
U. Germann
,
Priscilla Wu Cheng
,
I. Pastan
,
Michael M. Gottesman
Biochemistry
1999
Corpus ID: 25589411
Human P-glycoprotein (P-gp) is a cell surface drug efflux pump that contains two nucleotide binding domains (NBDs). Mutations…
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Highly Cited
1998
Highly Cited
1998
Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport.
C. Hrycyna
,
Lisa E. Airan
,
U. Germann
,
S. Ambudkar
,
I. Pastan
,
M. Gottesman
Biochemistry
1998
Corpus ID: 2788483
P-Glycoprotein (Pgp), an energy-dependent drug efflux pump responsible for multidrug resistance of many cancer cells, is…
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Highly Cited
1993
Highly Cited
1993
Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein.
M. Al-Shawi
,
A. E. Senior
Journal of Biological Chemistry
1993
Corpus ID: 7293538
Highly Cited
1992
Highly Cited
1992
Unfolded proteins stimulate molecular chaperone Hsc70 ATPase by accelerating ADP/ATP exchange.
S. Sadis
,
L. Hightower
Biochemistry
1992
Corpus ID: 25636897
The mammalian 70-kilodalton heat shock cognate protein (Hsc70) is an abundant, cytosolic molecular chaperone whose interactions…
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Highly Cited
1990
Highly Cited
1990
Temporary contractile blockade prevents hypercontracture in anoxic-reoxygenated cardiomyocytes.
B. Siegmund
,
T. Klietz
,
P. Schwartz
,
H. Piper
American Journal of Physiology
1990
Corpus ID: 25312333
Highly Cited
1989
Highly Cited
1989
Reconstitution of a bacterial periplasmic permease in proteoliposomes and demonstration of ATP hydrolysis concomitant with transport.
L. Bishop
,
Romeo Agbayani
,
S. Ambudkar
,
P. Maloney
,
G. Ames
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 23853818
The histidine periplasmic permease of Salmonella typhimurium has been partially purified and reconstituted into proteoliposomes…
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Highly Cited
1976
Highly Cited
1976
Mechanism of ATP hydrolysis by sarcoplasmic reticulum and the role of phospholipids.
H. Nakamura
,
R. Jilka
,
R. Boland
,
A. Martonosi
Journal of Biological Chemistry
1976
Corpus ID: 230498
Exchange of sarcoplasmic reticulum phospholipids with dipalmitoyllecithin inhibits the (Mg2+ + Ca2+)-activated ATPase activity…
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Highly Cited
1975
Highly Cited
1975
Respiratory control in isolated perfused rat heart. Role of the equilibrium relations between the mitochondrial electron carriers and the adenylate system.
I. E. Hassinen
,
Kalervo Hiltunen
Biochimica et Biophysica Acta
1975
Corpus ID: 24392694
Highly Cited
1973
Highly Cited
1973
Stoichiometry of adenosine triphosphate-driven proton translocation in bovine heart submitochondrial particles.
W. S. Thayer
,
P. C. Hinkle
Journal of Biological Chemistry
1973
Corpus ID: 934976
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