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IFIH1 wt Allele

Known as: RH116, Hlcd, AGS7 
Human IFIH1 wild-type allele is located in the vicinity of 2q24 and is approximately 52 kb in length. This allele, which encodes interferon-induced… 
National Institutes of Health

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AICARDI-GOUTIERES SYNDROME 7ATP HydrolysisAntiviral ResponseDNA Repair

Broader (1)

IFIH1 gene

Papers overview

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2017
2017
DEC 1 negatively regulates the expression of CXCL 10 and CCL 5 induced by poly IC in normal human mesangial cells
The functions of differentiated embryonic chondrocyte gene (DEC) 1, a basic helix-loop-helix (bHLH) transcription factor, have… 
2016
2016
[The laboratory detection of intra-cellular factors of anti-viral defense under community-acquired pneumonia in evaluation of effects of low-intensity microwave radiation].
The study was carried out to investigate intro-cellular concentration of factors of antiviral defense of cells of whole blood of… 
2016
2016
Progress on study of RIG-I and MDA5 in RLRs family
2015
2015
MDA5 and a type 1 interferon signature in the development of type 1 diabetes
2014
2014
RIG-I dependent sensing of poly ( dAdT ) via the induction of an RNA polymerase III transcribed RNA intermediate
Viral RNA is sensed by TLR 7 and 8 or by the RNA helicases LGP2, MDA5 and RIG-I to trigger antiviral responses. Much less is… 
2014
2014
Bursal transcriptome of chickens protected by DNA vaccination versus those challenged with infectious bursal disease virus
Infectious bursal disease virus (IBDV) infection destroys the bursa of Fabricius, causing immunosuppression and rendering… 
2013
2013
Cytokine gene expression in human hepatocytes infected with dengue virus serotype 3 (strain-16562)
Liver is a site of viral replication and liver dysfunction is a characteristic of severe dengue infection. To understand these… 
2010
2010
Evasion of RIG-I/MDA5 and TLR3-mediated innate immunity by hepatitis A virus
2010
2010
Zebrafish MDA5 is Essential for a Vigorous Antiviral Response to Rhabdovirus Infection
2010
2010
Papel do PTPN2 e MDA5, dois genes candidatos para diabete melito tipo 1, nas respostas das células beta pancreáticas a citocinas pró-­‐inflamatórias e ao RNA de fita dupla intracelular
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