IFIH1 wt Allele

Known as: RH116, Hlcd, AGS7 
Human IFIH1 wild-type allele is located in the vicinity of 2q24 and is approximately 52 kb in length. This allele, which encodes interferon-induced… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2017
010203019912017

Papers overview

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Highly Cited
2013
Highly Cited
2013
RIG-I and MDA5 have emerged as key cytosolic sensors for the detection of RNA viruses and lead to antiviral interferon (IFN… (More)
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2012
2012
RIG-I and MDA5 are cytosolic RNA sensors that play a critical role in innate antiviral responses. Major advances have been made… (More)
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Highly Cited
2011
Highly Cited
2011
The type I interferon response protects cells against invading viral pathogens. The cellular factors that mediate this defence… (More)
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Highly Cited
2011
Highly Cited
2011
Dengue virus (DV) infection is one of the most common mosquito-borne viral diseases in the world. The innate immune system is… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVES Myositis-specific autoantibodies are useful for diagnosing PM/DM. Recently, two new myositis-specific autoantibodies… (More)
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Highly Cited
2009
Highly Cited
2009
The double-stranded RNA (dsRNA) analogue poly(I:C) is a promising adjuvant for cancer vaccines because it activates both… (More)
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Highly Cited
2008
Highly Cited
2008
Alpha/beta interferon immune defenses are essential for resistance to viruses and can be triggered through the actions of the… (More)
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Highly Cited
2008
Highly Cited
2008
RIG-I and MDA5, two related pathogen recognition receptors (PRRs), are known to be required for sensing various RNA viruses. Here… (More)
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Highly Cited
2008
Highly Cited
2008
The coronavirus mouse hepatitis virus (MHV) induces a minimal type I interferon (IFN) response in several cell types in vitro… (More)
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Highly Cited
2006
Highly Cited
2006
The innate immune system senses viral infection by recognizing a variety of viral components (including double-stranded (ds)RNA… (More)
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