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Growth factor mRNA and protein in preserved human amniotic membrane
TLDR
Preserved human AM expresses mRNAs for a number of growth factors and contains several growth factor proteins that might benefit epithelialization after AM transplantation, suggesting an epithelial origin for these growth factors.
HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis.
TLDR
While HLA-B*1502 is unlikely to be associated with carbamazepine-related or aromatic anti-epileptic agent-related SJS/TEN in Japanese, HLA*5801 was significantly associated with allopurinol- related S JS/T EN in Japanese.
Transplantation of cultivated autologous oral mucosal epithelial cells in patients with severe ocular surface disorders
TLDR
Autologous oral epithelial cells grown on denuded amniotic membrane can be transplanted to treat severe ocular surface disorders and visual acuity was improved in all eyes.
Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene
TLDR
A new carbohydrate sulphotransferase gene (CHST6), encoding an enzyme designated corneal N-acetylglucosamine-6-sulphotranferase (C-GlcNAc6ST), is identified within the critical region of MCD type I, suggesting that mutations found in type II lead to loss of cornea-specific expression of CHST6.
HLA‐B*1511 is a risk factor for carbamazepine‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis in Japanese patients
TLDR
The genotyped the HLA‐B locus from 14 Japanese typical and atypical SJS/TEN patients in whom carbamazepine was considered to be involved in the onset of adverse reactions and suggested that HLA·B*1511, a member of HLA•B75, is a risk factor for carbamazepsine‐induced SJS /TEN in Japanese.
Dissemination of Methicillin-Resistant Staphylococci among Healthy Japanese Children
TLDR
The data indicated that MRSA clones distinct from H-MRSA have disseminated in healthy children, and the fact that MRC-NS strains were prevalent in the community suggested that they might serve as a reservoir for the SCCmec element carried by MRSA strains disseminatedIn the community.
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