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IAPP gene

Known as: IAPP, ISLET AMYLOID POLYPEPTIDE, DAP 
This gene plays a role in insulin-mediated glucose metabolism.
National Institutes of Health

Related topics

Related topics

5 relations
AmylinApoptosisIntercellular Communication ProcessIslet Amyloid Polypeptide, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Long-Term Metabolic and Hormonal Effects of Exenatide on Islet Transplant Recipients with Allograft Dysfunction
The initial success of islet transplantation (ITx) is followed by graft dysfunction (GDF) and insulin reintroduction. Exenatide… 
Highly Cited
2005
Highly Cited
2005
The role of amylin and glucagon in the dampening of glycemic excursions in children with type 1 diabetes.
Postprandial hyperglycemia and preprandial hypoglycemia contribute to poor glycemic control in type 1 diabetes. We hypothesized… 
Highly Cited
2004
Highly Cited
2004
Amylin receptor blockade stimulates food intake in rats.
Amylin is postulated to act as a hormonal signal from the pancreas to the brain to inhibit food intake and regulate energy… 
Highly Cited
2002
Highly Cited
2002
Inhibition of amyloid fibril formation of human amylin by N-alkylated amino acid and alpha-hydroxy acid residue containing peptides.
Amyloid deposits are formed as a result of uncontrolled aggregation of (poly)peptides or proteins. Today several diseases are… 
Highly Cited
2002
Highly Cited
2002
Insulin and amylin release are both diminished in first-degree relatives of subjects with type 2 diabetes.
OBJECTIVE To determine whether first-degree relatives of individuals with type 2 diabetes, who are at high risk of subsequently… 
Highly Cited
2000
Highly Cited
2000
Chromosome instability contributes to loss of heterozygosity in mice lacking p53.
The p53 tumor suppressor protein participates in multiple cellular processes including cell cycle checkpoints and programmed cell… 
Highly Cited
1995
Highly Cited
1995
Gastric emptying is accelerated in diabetic BB rats and is slowed by subcutaneous injections of amylin
SummaryGastric emptying was measured in normal and insulin-treated spontaneously diabetic BB rats using the retention of an… 
Highly Cited
1994
Highly Cited
1994
Direct plasma radioimmunoassay for rat amylin-(1-37): concentrations with acquired and genetic obesity.
Amylin (islet-associated polypeptide) is a 37-amino acid peptide that is cosecreted with insulin from the pancreatic beta-cell… 
Highly Cited
1990
Highly Cited
1990
The demonstration of vasodilator activity of pancreatic amylin amide in the rabbit.
Amylin amide, a 37-amino acid peptide that is a major component of amyloid deposits in the diabetic pancreas, possesses… 
Highly Cited
1990
Highly Cited
1990
Islet amyloid polypeptide (IAPP;amylin) influences the endocrine but not the exocrine rat pancreas.
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