Islet Amyloid Polypeptide, human

Known as: Insulinoma Amyloid Peptide, Amylin, Diabetes-Associated Peptide 
Islet amyloid polypeptide (89 aa, ~10 kDa) is encoded by the human IAPP gene. This protein plays a role in the regulation of glucose metabolism.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
We study the problem of object recognition for categories for which we have no training examples, a task also called zero--data… (More)
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Highly Cited
2008
Highly Cited
2008
Human islet amyloid polypeptide (IAPP or amylin) is a 37-residue hormone found as fibrillar deposits in pancreatic extracts of… (More)
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Highly Cited
2008
Highly Cited
2008
We describe a full structural model for amyloid fibrils formed by the 40-residue beta-amyloid peptide associated with Alzheimer's… (More)
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Highly Cited
2005
Highly Cited
2005
Protein conformational diseases, including Alzheimer's, Huntington's, and Parkinson's diseases, result from protein misfolding… (More)
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Review
2004
Review
2004
Autophagy is characterized by sequestration of bulk cytoplasm and organelles in double or multimembrane autophagic vesicles, and… (More)
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Highly Cited
2001
Highly Cited
2001
The development of type II diabetes was shown to be associated with the formation of amyloid fibrils consisted of the islet… (More)
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Review
1999
Review
1999
Islet amyloid has been recognized as a pathological entity in type 2 diabetes since the turn of the century. It has as its unique… (More)
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Highly Cited
1996
Highly Cited
1996
Pancreatic islet amyloid deposits are a characteristic pathologic feature of non-insulin-dependent diabetes mellitus and contain… (More)
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Highly Cited
1987
Highly Cited
1987
Deposition of amyloid in pancreatic islets is a common feature in human type 2 diabetic subjects but because of its insolubility… (More)
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Highly Cited
1987
Highly Cited
1987
Pancreatic islet amyloid deposits were found in 22 of 24 type-2 diabetic subjects (aged 48-68 years) and were not present in 10… (More)
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