FAQ

Heterodimerization

Heterodimerization involves a biophysical interaction between two dissimilar biological molecules or subunits, such as between two proteins. The… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
05101519902018

Related topics

Related topics

12 relations
DNA-Binding Protein Inhibitor ID-3ID3 geneID3 wt AlleleID4 protein, human
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Related mentions per year

Related mentions per year

1980-2018
19801990200020102020
Heterodimerization
ID3 gene
Myogenin
Integrin alpha4
ITGA6 gene
ITGA4 gene

Papers overview

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Highly Cited
2006
Highly Cited
2006
Regulation and role of Raf-1/B-Raf heterodimerization.
The Ras-Raf-MEK-extracellular signal-regulated kinase (ERK) pathway participates in the control of many fundamental cellular… (More)
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Highly Cited
2006
Highly Cited
2006
Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib.
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been used to treat non-small cell lung cancer… (More)
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Highly Cited
2004
Highly Cited
2004
Heterodimerization and endocytosis of Arabidopsis brassinosteroid receptors BRI1 and AtSERK3 (BAK1).
In Arabidopsis thaliana brassinosteroid (BR), perception is mediated by two Leu-rich repeat receptor-like kinases… (More)
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Highly Cited
2001
Highly Cited
2001
Chemokine receptor homo- or heterodimerization activates distinct signaling pathways.
Chemokine receptors of both the CC and CXC families have been demonstrated to undergo a ligand-mediated homodimerization process… (More)
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Highly Cited
2000
Highly Cited
2000
A Trafficking Checkpoint Controls GABAB Receptor Heterodimerization
Surface expression of GABA(B) receptors requires heterodimerization of GB1 and GB2 subunits, but little is known about mechanisms… (More)
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Highly Cited
2000
Highly Cited
2000
Heterodimerization of mu and delta opioid receptors: A role in opiate synergy.
Opiate analgesics are widely used in the treatment of severe pain. Because of their importance in therapy, different strategies… (More)
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Highly Cited
1998
Highly Cited
1998
Heterodimerization is required for the formation of a functional GABA(B) receptor.
GABA (gamma-aminobutyric acid) is the main inhibitory neurotransmitter in the mammalian central nervous system, where it exerts… (More)
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Highly Cited
1997
Highly Cited
1997
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling.
We have analyzed ErbB receptor interplay induced by the epidermal growth factor (EGF)-related peptides in cell lines naturally… (More)
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Highly Cited
1993
Highly Cited
1993
Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle.
Ecdysone in Drosophila has been a paradigm for steroid hormones since its ability to induce gene activity directly was… (More)
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Highly Cited
1993
Highly Cited
1993
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation.
The E2F transcription factor has been implicated in the regulation of genes whose products are involved in cell proliferation… (More)
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