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ID3 gene

Known as: HEIR-1, inhibitor of differentiation 3, Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein Gene 
This gene plays a role in transcriptional repression.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Burkitt lymphoma is a mature aggressive B-cell lymphoma derived from germinal center B cells. Its cytogenetic hallmark is the… Expand
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Highly Cited
2012
Highly Cited
2012
There is increasing evidence that some cancers are hierarchically organized, sustained by a relatively rare population of cancer… Expand
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Highly Cited
2012
Highly Cited
2012
Burkitt lymphoma is characterized by deregulation of MYC, but the contribution of other genetic mutations to the disease is… Expand
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Highly Cited
2011
Highly Cited
2011
The transcriptional repressor Blimp-1 promotes the differentiation of CD8+ T cells into short-lived effector cells (SLECs) that… Expand
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Highly Cited
2011
Highly Cited
2011
Aberrant activation of receptor tyrosine kinases (RTK) is causally linked to the pathobiological traits of glioblastoma and… Expand
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Highly Cited
2006
Highly Cited
2006
FOP is a disabling disorder in which skeletal muscle is progressively replaced with bone. Lymphocytes, our model system for… Expand
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Highly Cited
2001
Highly Cited
2001
E proteins function in many developmental processes and are essential for the formation of lymphocyte progenitors. However, it is… Expand
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Highly Cited
2000
Highly Cited
2000
Unliganded thyroid hormone receptors (TRs) repress transcription through recruitment of corepressors, including nuclear receptor… Expand
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Highly Cited
1999
Highly Cited
1999
Id proteins act as negative regulators of bHLH transcription factors by forming transcriptionally inactive protein complexes. The… Expand
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Highly Cited
1996
Highly Cited
1996
Cells which are highly proliferative typically lack expression of differentiated, lineage-specific characteristics. Id2, a member… Expand
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