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Heparin Lyase

Known as: Eliminase, Heparin, Heparinase, Lyase, Heparin 
An enzyme of the isomerase class that catalyzes the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate… 
National Institutes of Health

Related topics

Related topics

12 relations
BacteriaIn BloodLyaseProcess of secretion

Broader (1)

Polysaccharide-Lyases

Narrower (2)

acharan sulfate lyase 1acharan sulfate lyase 2

Papers overview

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Highly Cited
2001
Highly Cited
2001
Echoviruses Bind Heparan Sulfate at the Cell Surface
ABSTRACT Some echoviruses (EV) that bind decay-accelerating factor (DAF) also bind cells of human and murine origins in a DAF… 
Highly Cited
1998
Highly Cited
1998
Differential Cellular Accumulation/Retention of Apolipoprotein E Mediated by Cell Surface Heparan Sulfate Proteoglycans
Isoform-specific effects of apolipoprotein E (apoE) on neurite outgrowth and the cytoskeleton are associated with higher… 
Highly Cited
1996
Highly Cited
1996
Sulfated polyanions inhibit invasion of erythrocytes by plasmodial merozoites and cytoadherence of endothelial cells to parasitized erythrocytes
Sulfated proteoglycans have been shown to be involved in the binding of sporozoites of malaria parasites to hepatocytes. In this… 
Highly Cited
1994
Highly Cited
1994
Heparan sulfate proteoglycans are required for mesoderm formation in Xenopus embryos.
Mesoderm forms in the vertebrate embryo as a result of inductive interactions involving secreted growth factors and cell surface… 
Highly Cited
1989
Highly Cited
1989
Intraocular PMMA lenses modified with surface-immobilized heparin: evaluation of biocompatibility in vitro and in vivo.
Highly Cited
1987
Highly Cited
1987
Activation of heparin cofactor II by fibroblasts and vascular smooth muscle cells.
Highly Cited
1985
Highly Cited
1985
Heparinlike molecules with anticoagulant activity are synthesized by cultured endothelial cells.
Highly Cited
1985
Highly Cited
1985
Interaction of antithrombin III with bovine aortic segments. Role of heparin in binding and enhanced anticoagulant activity.
Bovine antithrombin III (AT III) interaction with the luminal surface of bovine aortic segments with a continuous layer of… 
Highly Cited
1985
Highly Cited
1985
High-performance liquid chromatographic separation of heparin-derived oligosaccharides.
Highly Cited
1981
Highly Cited
1981
Proteoglycans in the microvasculature. I. Histochemical localization in microvessels of the rabbit eye.
The ultrastructural organization of ruthenium red (RR) stainable material within small blood vessels located in the limbus of the… 
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