Heparin Lyase

Known as: Eliminase, Heparin, Heparinase, Lyase, Heparin 
An enzyme of the isomerase class that catalyzes the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
020406019512017

Papers overview

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Highly Cited
2007
Highly Cited
2007
The plasma membrane represents an impermeable barrier for most macromolecules. Still some proteins and so-called cell-penetrating… (More)
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Highly Cited
2003
Highly Cited
2003
The objective of this study was to test whether a glycosaminoglycan component of the surface glycocalyx layer is a fluid shear… (More)
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Highly Cited
2001
Highly Cited
2001
Using pseudoinfection of cell lines, we demonstrate that cell surface heparan sulfate is required for infection by human… (More)
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Highly Cited
1997
Highly Cited
1997
OBJECTIVE To analyze the mechanisms of release and the extracellular fate of the HIV-1 Tat protein and to determine the Tat… (More)
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Highly Cited
1997
Highly Cited
1997
A vascular endothelial growth factor (VEGF) mRNA species containing exons 1-6 and 8 of the VEGF gene was found to be expressed as… (More)
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Highly Cited
1996
Highly Cited
1996
Foot-and-mouth disease virus (FMDV) enters cells by attaching to cellular receptor molecules of the integrin family, one of which… (More)
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Highly Cited
1995
Highly Cited
1995
IP-10 is a member of the chemokine family of cytokines and is induced in a variety of cells in response to interferon gamma and… (More)
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Highly Cited
1992
Highly Cited
1992
The vascular endothelial growth factor (VEGF) family encompasses four polypeptides that result from alternative splicing of mRNA… (More)
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Highly Cited
1988
Highly Cited
1988
Cultured bovine capillary endothelial (BCE) cells were found to synthesize and secrete high molecular mass heparan sulfate… (More)
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Highly Cited
1980
Highly Cited
1980
Glomerular basement membranes (GBM's) were subjected to digestion in situ with glycosaminoglycan-degrading enzymes to assess the… (More)
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