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Heparin Lyase

Known as: Eliminase, Heparin, Heparinase, Lyase, Heparin 
An enzyme of the isomerase class that catalyzes the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Significance Prion-like propagation of proteopathic seeds may underlie the progression of neurodegenerative diseases, including… Expand
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Highly Cited
2011
Highly Cited
2011
INTRODUCTION Blood transfusion is associated with increased morbidity and mortality. We developed and implemented an algorithm… Expand
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Highly Cited
2007
Highly Cited
2007
The plasma membrane represents an impermeable barrier for most macromolecules. Still some proteins and so-called cell-penetrating… Expand
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Highly Cited
2003
Highly Cited
2003
Abstract— The objective of this study was to test whether a glycosaminoglycan component of the surface glycocalyx layer is a… Expand
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Highly Cited
2002
Highly Cited
2002
Basic peptides such as human immunodeficiency virus type 1 (HIV-1) Tat-(48–60) and DrosophilaAntennapedia-(43–58) have been… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT Using pseudoinfection of cell lines, we demonstrate that cell surface heparan sulfate is required for infection by human… Expand
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Highly Cited
1997
Highly Cited
1997
A vascular endothelial growth factor (VEGF) mRNA species containing exons 1-6 and 8 of the VEGF gene was found to be expressed as… Expand
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Highly Cited
1996
Highly Cited
1996
We report evidence that gene complexes, consisting of polycations and plasmid DNA enter cells via binding to membrane-associated… Expand
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Highly Cited
1996
Highly Cited
1996
Perlecan is a modular heparan sulfate proteoglycan that is localized to cell surfaces and within basement membranes. Its ability… Expand
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Highly Cited
1992
Highly Cited
1992
The vascular endothelial growth factor (VEGF) family encompasses four polypeptides that result from alternative splicing of mRNA… Expand
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