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Heparan Sulfate Proteoglycans

Known as: HSPG, Heparan sulfate proteoglycan, Heparan Sulfate Proteoglycans [Chemical/Ingredient] 
Heparan Sulfate Proteoglycan is an extracellular matrix and vascular basal lamina component. Heparan Sulfate is also an essential co-factor in cell… 
National Institutes of Health

Related topics

Related topics

23 relations
Basement Membrane-Specific Heparan Sulfate Proteoglycan Core ProteinCell-Matrix JunctionExtracellular MatrixHSPG2 gene

Broader (1)

Heparitin Sulfate

Narrower (4)

endorepellin protein, humankny protein, zebrafishperlecantrol protein, Drosophila

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis.
Arginine-rich peptides, including octaarginine (R8), HIV-1 Tat, and branched-chain arginine-rich peptides, belong to one of the… 
Highly Cited
2007
Highly Cited
2007
Hepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycans.
UNLABELLED Contrary to many other viruses, the initial steps of the hepatitis B virus (HBV) infection, including attachment to… 
Highly Cited
2004
Highly Cited
2004
Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans
The signaling molecules Hedgehog (Hh), Decapentaplegic (Dpp) and Wingless (Wg) function as morphogens and organize wing… 
Highly Cited
2003
Highly Cited
2003
QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling
The 6-O sulfation states of cell surface heparan sulfate proteoglycans (HSPGs) are dynamically regulated to control the growth… 
Highly Cited
2001
Highly Cited
2001
Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless.
Recent studies in Drosophila have shown that heparan sulfate proteoglycans (HSPGs) are required for Wingless (Wg/Wnt) signaling… 
Review
2001
Review
2001
Heparan sulfate proteoglycans in invasion and metastasis.
Because heparan sulfate proteoglycans mediate cell adhesion and control the activities of numerous growth and motility factors… 
Review
2000
Review
2000
Regulation of angiogenesis via vascular endothelial growth factor receptors.
Endothelial cell signal transduction mechanisms involved in angiogenesis have come into focus in cancer research when it was… 
Highly Cited
1995
Highly Cited
1995
The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation
IP-10 is a member of the chemokine family of cytokines and is induced in a variety of cells in response to interferon gamma and… 
Highly Cited
1994
Highly Cited
1994
Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns.
The syndecans are a gene family of four transmembrane heparan sulfate proteoglycans that bind, via their HS chains, diverse… 
Highly Cited
1993
Highly Cited
1993
Developmental regulation of neural response to FGF-1 and FGF-2 by heparan sulfate proteoglycan.
Murine neural precursor cells and cell lines derived from them are stimulated by members of the heparin-binding fibroblast growth… 
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