Skip to search formSkip to main contentSkip to account menu

HNF1A gene

Known as: ALBUMIN PROXIMAL FACTOR, LFB1, HNF1 Homeobox A Gene 
This gene plays a role in both DNA binding and transcriptional modulation.
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (1)

HNF1A wt Allele
Hepatocyte Nuclear Factor 1Hepatocyte Nuclear Factor 1-alphaHomo sapiensTranscriptional Activation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Integrative Bioinformatics Links HNF1B with Clear Cell Carcinoma and Tumor-Associated Thrombosis
Clear cell carcinoma (CCC) is a histologically distinct carcinoma subtype that arises in several organ systems and is marked by… 
Review
2005
Review
2005
UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects.
Highly Cited
2001
Highly Cited
2001
Inhibitory Cross-talk between STAT5b and Liver Nuclear Factor HNF3β
STAT5b is repeatedly activated in rodent liver by the male pattern of intermittent plasma growth hormone (GH) stimulation and is… 
Highly Cited
1997
Highly Cited
1997
A hepatitis B virus mutant with a new hepatocyte nuclear factor 1 binding site emerging in transplant‐transmitted fulminant hepatitis B
Hepatitis B virus (HBV) DNA was cloned from serum of a heart transplant recipient who died from fulminant hepatitis B transmitted… 
Highly Cited
1996
Highly Cited
1996
Multiple Factors Regulate the Rat Liver Basolateral Sodium-dependent Bile Acid Cotransporter Gene Promoter*
The hepatic uptake of bile acids from the portal circulation is primarily dependent upon a sodium-dependent basolateral membrane… 
Highly Cited
1993
Highly Cited
1993
Analysis of the rat hepatocyte nuclear factor (HNF) 1 gene promoter: synergistic activation by HNF4 and HNF1 proteins.
Hepatocyte nuclear factor (HNF) 1 is a key transcription factor involved in the expression of many liver-specific genes. We have… 
Highly Cited
1992
Highly Cited
1992
Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I gene.
Systematic mutational analysis previously identified two primary regulatory elements within a minienhancer (-247 to -198) of the… 
Highly Cited
1991
Highly Cited
1991
Promoter-specific transactivation of hepatitis B virus transcription by a glutamine- and proline-rich domain of hepatocyte nuclear factor 1
The cloned transcription factor hepatocyte nuclear factor 1 (HNF1) transactivates transcription from the hepatitis B virus (HBV… 
Highly Cited
1990
Highly Cited
1990
Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of…
Several distinct octamer-binding transcription factors (OTFs) interact with the sequence ATTTGCAT (the octamer motif), which acts… 
Highly Cited
1990
Highly Cited
1990
Differentiation-specific transcriptional regulation of the hepatitis B virus large surface antigen gene in human hepatoma cell lines
The transcriptional activities of the four hepatitis B virus promoters were compared in three differentiated hepatoma cell lines… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)