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HNF1A wt Allele

Known as: IDDM20, LFB1, Interferon Production Regulator Factor Gene 
Human HNF1A wild-type allele is located in the vicinity of 12q22-qter; 12q24.2 and is approximately 25 kb in length. This allele, which encodes… 
National Institutes of Health

Related topics

Related topics

10 relations
ALK PathwayGrowth Hormone Signaling PathwayHepatocyte Nuclear Factor 1-alphaHomo sapiens

Broader (1)

HNF1A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Low prevalence of MODY2 and MODY3 mutations in Brazilian individuals with clinical MODY phenotype.
2003
2003
HNF-1alpha and endodermal transcription factors cooperatively activate Fabpl: MODY3 mutations abrogate cooperativity.
Hepatocyte nuclear factor (HNF)-1alpha plays a central role in intestinal and hepatic gene regulation and is required for hepatic… 
2002
2002
Expression profile of MODY3/HNF-1α protein in the developing mouse pancreas
HeadingAbstract Aims/hypothesis. One subtype of MODY (MODY3) results from the heterozygous mutation of a hepatocyte nuclear… 
2002
2002
Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency
Apc (adenomatous polyposis coli) encodes a tumour suppressor gene that is mutated in the majority of colorectal cancers. Recent… 
2002
2002
Expression profile of MODY3/HNF-1alpha protein in the developing mouse pancreas.
AIMS/HYPOTHESIS One subtype of MODY (MODY3) results from the heterozygous mutation of a hepatocyte nuclear factor (HNF)-1alpha… 
Highly Cited
2001
Highly Cited
2001
Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations
Aims/hypothesis. The aim of this study was to examine the putative role of mutations in the insulin promoter 1 (IPF1) gene in… 
Highly Cited
1997
Highly Cited
1997
Genetic variation in the hepatocyte nuclear factor-1a gene in Danish Caucasians with late-onset NIDDM
Summary Non-insulin-dependent diabetes mellitus (NIDDM) is a phenotypically and genetically heterogeneous disorder. A recent… 
1996
1996
Human renal cell carcinogenesis is accompanied by a coordinate loss of the tissue specific transcription factors HNF4 alpha and HNF1 alpha.
Human renal cell carcinogenesis is usually accompanied by dedifferentiation processes including the loss of expression of tissue… 
1995
1995
Developmental expression of the maternal protein XDCoH, the dimerization cofactor of the homeoprotein LFB1 (HNF1).
The tissue-specific transcription factors LFB1 (HNF1) and LFB3 (vHNF1) mainly expressed in liver, kidney and intestine are… 
Highly Cited
1993
Highly Cited
1993
HNF4 and HNF1 as well as a panel of hepatic functions are extinguished and reexpressed in parallel in chromosomally reduced rat hepatoma-human fibroblast hybrids
Rat hepatoma-human fibroblast hybrids of two independent lineages containing only 8-11 human chromosomes show pleiotropic… 
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