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Crypt stem cells as the cells-of-origin of intestinal cancer
- N. Barker, R. Ridgway, H. Clevers
- BiologyNature
- 29 January 2009
TLDR
Requirement for a functional Rb-1 gene in murine development
- A. Clarke, E. R. Maandag, Hein te Rielef
- BiologyNature
- 24 September 1992
TLDR
Thymocyte apoptosis induced by p53-dependent and independent pathways
TLDR
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.
TLDR
Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages
- P. Mombaerts, A. Clarke, S. Tonegawa
- BiologyNature
- 19 November 1992
Analysis of mice carrying mutant T-cell antigen receptor (TCP) genes indicates that TCP-β gene rearrangement or expression is critical for the differentiation of CD4− CD8− thymocytes to CD4+CD8+…
Myc deletion rescues Apc deficiency in the small intestine
TLDR
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages.
- P. Mombaerts, A. Clarke, M. Hooper
- BiologyNature
- 1992
Analysis of mice carrying mutant T-cell antigen receptor (TCR) genes indicates that TCR-beta gene rearrangement or expression is critical for the differentiation of CD4-CD8- thymocytes to CD4+CD8+…
Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.
- R. Chapman, P. Lourenço, C. Watson
- BiologyGenes & development
- 1 October 1999
TLDR
129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal
- J. Manson, A. Clarke, M. Hooper, L. Aitchison, I. Mcconnell, J. Hope
- BiologyMolecular Neurobiology
- 1 April 1994
TLDR
Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin.
- H. Ireland, Richard Kemp, D. Winton
- BiologyGastroenterology
- 1 May 2004
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