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Hepatocyte Nuclear Factor 1-alpha

Known as: Hepatocyte Nuclear Factor 1-alpha [Chemical/Ingredient], Liver Specific Transcription Factor LF B1, Liver-Specific Transcription Factor LF-B1 
Hepatocyte nuclear factor 1-alpha (631 aa, ~67 kDa) is encoded by the human HNF1A gene. This protein plays a role in transcriptional regulation.
National Institutes of Health

Related topics

Related topics

23 relations
ALK PathwayCell NucleusDNA-Binding ProteinsGenes, Regulator

Papers overview

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Highly Cited
2010
Highly Cited
2010
Regulation of the heat shock response under anoxia in the turtle, Trachemys scripta elegans
The effects of 20 h of anoxic submergence in cold water and 5 h of aerobic recovery on the heat shock response were analyzed in… 
2008
2008
Hepatocyte nuclear factor-4alpha promotes differentiation of intestinal epithelial cells in a coculture system.
Normal cellular models able to efficiently recapitulate intestinal epithelial cell differentiation in culture are not yet… 
Highly Cited
2004
Highly Cited
2004
Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4.
Lactase-phlorizin hydrolase (LPH), a marker of intestinal differentiation, is expressed in absorptive enterocytes on small… 
Highly Cited
2004
Highly Cited
2004
Quantitative gene expression profiling reveals a fetal hepatic phenotype of murine ES-derived hepatocytes.
To use embryonic stem (ES) cells in future therapeutical applications, differentiated hepatic phenotypes with specific liver… 
Highly Cited
2003
Highly Cited
2003
Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1alpha)-deficient mice.
Highly Cited
2002
Highly Cited
2002
Regulation of kidney-specific Ksp-cadherin gene promoter by hepatocyte nuclear factor-1beta.
Kidney-specific cadherin (Ksp-cadherin) is a tissue-specific member of the cadherin family that is expressed exclusively in the… 
Highly Cited
2000
Highly Cited
2000
Fibronectin regulates morphology, cell organization and gene expression of rat fetal hepatocytes in primary culture.
Highly Cited
1997
Highly Cited
1997
Protein Kinase A Activation of the Surfactant Protein B Gene Is Mediated by Phosphorylation of Thyroid Transcription Factor 1*
Thyroid transcription factor 1 (TTF-1) is a homeodomain-containing nuclear transcription factor expressed in epithelial cells of… 
1993
1993
Elements and factors involved in tissue-specific and embryonic expression of the liver transcription factor LFB1 in Xenopus laevis
LFB1 (HNF1) is a tissue-specific transcription factor found in the livers, stomachs, intestines, and kidneys of vertebrates. By… 
Highly Cited
1992
Highly Cited
1992
Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I gene.
Systematic mutational analysis previously identified two primary regulatory elements within a minienhancer (-247 to -198) of the… 
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