Hepatocyte Nuclear Factor 1-alpha

Known as: Hepatocyte Nuclear Factor 1-alpha [Chemical/Ingredient], Liver Specific Transcription Factor LF B1, Liver-Specific Transcription Factor LF-B1 
Hepatocyte nuclear factor 1-alpha (631 aa, ~67 kDa) is encoded by the human HNF1A gene. This protein plays a role in transcriptional regulation.

Topic mentions per year

Topic mentions per year

1985-2017
020406019852017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Growing evidence indicates that microRNAs have a significant role in tumor development and may constitute robust biomarkers for… (More)
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Highly Cited
2009
Highly Cited
2009
CONTEXT Plasma levels of C-reactive protein (CRP) are independently associated with risk of coronary heart disease, but whether… (More)
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Highly Cited
2008
Highly Cited
2008
Data from the Pharmacogenomics and Risk of Cardiovascular Disease (PARC) study and the Cardiovascular Health Study (CHS) provide… (More)
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Highly Cited
2008
Highly Cited
2008
Although elevated levels of C-reactive protein (CRP) independently predict increased risk of development of metabolic syndrome… (More)
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Highly Cited
2007
Highly Cited
2007
We demonstrate that the binding sites for highly conserved transcription factors vary extensively between human and mouse. We… (More)
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Highly Cited
2006
Highly Cited
2006
Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes mellitus characterized by autosomal dominant… (More)
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Highly Cited
2002
Highly Cited
2002
We have derived from normal human, mouse, and rat postnatal bone marrow primitive, multipotent adult progenitor cells (MAPCs… (More)
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Highly Cited
2000
Highly Cited
2000
HNF-4alpha is a transcription factor of the nuclear hormone receptor family that is expressed in the hepatic diverticulum at the… (More)
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Highly Cited
1996
Highly Cited
1996
The disease maturity-onset diabetes of the young (MODY) is a genetically heterogeneous monogenic form of non-insulin-dependent… (More)
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Highly Cited
1996
Highly Cited
1996
The disease non-insulin-dependent (type 2) diabetes mellitus (NIDDM) is characterized by abnormally high blood glucose resulting… (More)
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