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Transcriptional Activation

Known as: Up-Regulation, Activation, Transcription, Transcription Activation 
The process by which an unexpressed gene is activated to serve as a transcription template for synthesis of RNA.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Systematic interrogation of gene function requires the ability to perturb gene expression in a robust and generalizable manner… Expand
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Highly Cited
2007
Highly Cited
2007
AU-rich elements (AREs) and microRNA target sites are conserved sequences in messenger RNA (mRNA) 3′ untranslated regions (3′UTRs… Expand
Highly Cited
2003
Highly Cited
2003
Hypoxia unleashes the invasive and metastatic potential of tumor cells by largely unknown mechanisms. The Met tyrosine kinase, a… Expand
Review
2002
Review
2002
  • A. Bird
  • Genes & development
  • 2002
  • Corpus ID: 11818723
The character of a cell is defined by its constituent proteins, which are the result of specific patterns of gene expression… Expand
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Highly Cited
1997
Highly Cited
1997
The adenomatous polyposis coli (APC) tumor suppressor protein binds to β-catenin, a protein recently shown to interact with Tcf… Expand
Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor alpha (TNF alpha) is a potent immunomodulator and proinflammatory cytokine that has been implicated in the… Expand
Highly Cited
1995
Highly Cited
1995
The c-fos serum response element (SRE) forms a ternary complex with the transcription factors SRF (serum response factor) and TCF… Expand
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Review
1994
Review
1994
Through the study of transcriptional activation in response to interferon alpha (IFN-alpha) and interferon gamma (IFN-gamma), a… Expand
Highly Cited
1992
Highly Cited
1992
We have identified a 50-nucleotide enhancer from the human erythropoietin gene 3'-flanking sequence which can mediate a sevenfold… Expand
Highly Cited
1989
Highly Cited
1989
We have previously reported the presence of a hormone-inducible transcriptional activation function (TAF-2) within the region of… Expand