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Transcriptional Activation

Known as: Up-Regulation, Activation, Transcription, Transcription Activation 
The process by which an unexpressed gene is activated to serve as a transcription template for synthesis of RNA.
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Apoptosis is a form of cell death by which the body maintains the homeostasis of the internal environment. Apoptosis is an… Expand
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Highly Cited
2015
Highly Cited
2015
Systematic interrogation of gene function requires the ability to perturb gene expression in a robust and generalizable manner… Expand
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Highly Cited
2007
Highly Cited
2007
AU-rich elements (AREs) and microRNA target sites are conserved sequences in messenger RNA (mRNA) 3′ untranslated regions (3′UTRs… Expand
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Highly Cited
2006
Highly Cited
2006
Recent studies have shown that small noncoding RNAs, such as microRNAs and siRNAs, regulate gene expression at multiple levels… Expand
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Highly Cited
2003
Highly Cited
2003
Hypoxia unleashes the invasive and metastatic potential of tumor cells by largely unknown mechanisms. The Met tyrosine kinase, a… Expand
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Highly Cited
1997
Highly Cited
1997
The adenomatous polyposis coli (APC) tumor suppressor protein binds to β-catenin, a protein recently shown to interact with Tcf… Expand
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Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor alpha (TNF alpha) is a potent immunomodulator and proinflammatory cytokine that has been implicated in the… Expand
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Highly Cited
1995
Highly Cited
1995
The c-fos serum response element (SRE) forms a ternary complex with the transcription factors SRF (serum response factor) and TCF… Expand
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Review
1994
Review
1994
Through the study of transcriptional activation in response to interferon alpha (IFN-alpha) and interferon gamma (IFN-gamma), a… Expand
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Highly Cited
1992
Highly Cited
1992
We have identified a 50-nucleotide enhancer from the human erythropoietin gene 3'-flanking sequence which can mediate a sevenfold… Expand
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