FAQ

Alpha-Globin Transcription Factor CP2

Known as: Transcription Factor LSF, Late SV40 Factor, Transcription Factor CP2 
Alpha-globin transcription factor CP2 (502 aa, ~57 kDa) is encoded by the human TFCP2 gene. This protein plays a role in transcriptional activation.

Topic mentions per year

Topic mentions per year

1999-2017
0119992017

Related topics

Related topics

8 relations
Cell NucleusDNA-Binding ProteinsGenes, RegulatorTFCP2 gene
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Alpha-Globin Transcription Factor CP2
Cell Nucleus
dna binding
Genes, Regulator
Transcriptional Regulation
DNA-Binding Proteins

Papers overview

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2017
2017
Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A
Conventional therapeutic processes in patient with OSCC are associated with several unfavorable effects leading to patients with… (More)
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2016
2016
Transcription factor LSF (TFCP2) inhibits melanoma growth.
Late SV40 factor 3 (LSF), a transcription factor, contributes to human hepatocellular carcinoma (HCC). However, decreased… (More)
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2016
2016
Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression
The transcription factor LSF is highly expressed in hepatocellular carcinoma (HCC) and promotes oncogenesis. Factor quinolinone… (More)
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2015
2015
Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model
Hepatocellular carcinoma (HCC) is a lethal malignancy with high mortality and poor prognosis. Oncogenic transcription factor Late… (More)
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2012
2012
The transcription factor LSF: a novel oncogene for hepatocellular carcinoma.
The transcription factor LSF (Late SV40 Factor), also known as TFCP2, belongs to the LSF/CP2 family related to Grainyhead family… (More)
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2011
2011
c-Met activation through a novel pathway involving osteopontin mediates oncogenesis by the transcription factor LSF.
BACKGROUND & AIMS Understanding the molecular pathogenesis of hepatocellular carcinoma (HCC) would facilitate development of… (More)
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2010
2010
Transcription factor Late SV40 Factor (LSF) functions as an oncogene in hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is a highly aggressive cancer with no currently available effective treatment. Understanding of… (More)
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Review
2004
Review
2004
Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF.
Transcriptional regulation in mammalian cells is driven by a complex interplay of multiple transcription factors that respond to… (More)
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2002
2002
Regions and Represses Class Switching to IgA Protein Late SV40 Factor Binds Ig Switch The Ubiquitously Expressed DNA-Binding
 
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1999
1999
Purification and characterization of the serum amyloid A3 enhancer factor.
Serum amyloid A (SAA) is a major acute-phase protein synthesized and secreted mainly by the liver. In response to acute… (More)
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