Skip to search formSkip to main contentSkip to account menu

H2AFX gene

Known as: H2A HISTONE FAMILY, MEMBER X, H2AX, H2AFX 
This gene is involved in histone and nucleosome organization and chromatin compaction regulation.
National Institutes of Health

Related topics

Related topics

4 relations
Double Strand Break RepairH2AFX wt AlleleH2AX protein, humanV(D)J Recombination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
MicroRNA-138 inhibits tumor growth and enhances chemosensitivity in human cervical cancer by targeting H2AX
MicroRNA-138 (miR-138) acts as a key regulator in the modulation of carcinogenesis in numerous tumor types. Chemoresistance is… 
2013
2013
Heat stress induces ROS production and histone phosphorylation in celomocytes of Eisenia hortensis
The effect of heat stress on celomocytes (leukocytes) from Eisenia hortensis was investigated by measuring the production of… 
2013
2013
Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation
γH2AX formation by phosphorylation of the histone variant H2AX is the key process in the repair of DNA lesions including those… 
2012
2012
Suberoylanilide hydroxamic acid affects γH2AX expression in osteosarcoma, atypical teratoid rhabdoid tumor and normal tissue cell lines after irradiation
PurposeOsteosarcoma and atypical teratoid rhabdoid tumors are tumor entities with varying response to common standard therapy… 
Highly Cited
2009
Highly Cited
2009
Widespread Phosphorylation of Histone H2AX by Species C Adenovirus Infection Requires Viral DNA Replication
ABSTRACT Adenovirus infection activates cellular DNA damage response and repair pathways. Viral proteins that are synthesized… 
2008
2008
Autophosphorylation of H2AX in a cell-specific frozen dependent way.
2008
2008
Aberrant V(D)J recombination is not required for rapid development of H2ax/p53-deficient thymic lymphomas with clonal translocations.
Histone H2AX is required to maintain genomic stability in cells and to suppress malignant transformation of lymphocytes in mice… 
Highly Cited
2007
Highly Cited
2007
Collaborative roles of gammaH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair.
2007
2007
Histone H2AX phosphorylation is associated with most meiotic events in grasshopper
It is widely accepted that the H2AX histone in its phosphorylated form (γ-H2AX) is related to the repair of DNA double-strand… 
2003
2003
Absence of constitutional H2AX gene mutations in 101 hereditary breast cancer families
Several genes involved in the DNA damage response and in maintaining genomic stability have emerged as breast cancer… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)