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Natriuretic peptides are a family of structurally related but genetically distinct hormones/paracrine factors that regulate blood… Expand Nitric oxide (NO) was first recognized as a messenger molecule in the central nervous system (eNS) in 1988 (52), when it was… Expand NITRIC oxide is the major endothelium-derived relaxing factor (EDRF)1–3, and it is thought to relax smooth muscle cells by… Expand A potent, synthetic cannabinoid was radiolabeled and used to characterize and precisely localize cannabinoid receptors in slide… Expand Endothelium-derived relaxing factor has been recently identified as nitric oxide. The purpose of this study was to determine if… Expand Vertebrate rod photoreceptors hyperpolarize when illuminated, due to the closing of cation-selective channels in the plasma… Expand Previous observations that platelet guanosine 3’. 5’-monophosphate (cyclic GMP) accumulation occurred during platelet aggregation… Expand As a result of an early deficiency in cyclic nucleotide phosphodiesterase activity, guanosine 3',5'-monophosphate accumulates in… Expand In 1910, Bang' reported that concentrated solutions of guanylic acid formed a gel. We have also observed that concentrated… Expand