Guanine Nucleotides

Known as: Guanine Nucleotides [Chemical/Ingredient], Guanosine Phosphates, Phosphates, Guanosine 
 
National Institutes of Health

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19 relations

Narrower (9)

2',3'-cyclic GMP6-thioguanylic acidGuanosine DiphosphateGuanosine Monophosphate
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In BloodProcess of secretionagonistsantagonists & inhibitors
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Broader (2)

NADPPurine Nucleotides

Papers overview

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Review
2005
Review
2005
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
Guanine nucleotide-exchange factors (GEFs) are directly responsible for the activation of Rho-family GTPases in response to… (More)
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Review
2001
Review
2001
The guanine nucleotide-binding switch in three dimensions.
Guanine nucleotide-binding proteins regulate a variety of processes, including sensual perception, protein synthesis, various… (More)
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Highly Cited
2001
Highly Cited
2001
EphA Receptors Regulate Growth Cone Dynamics through the Novel Guanine Nucleotide Exchange Factor Ephexin
Eph receptors transduce short-range repulsive signals for axon guidance by modulating actin dynamics within growth cones. We… (More)
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Highly Cited
2000
Highly Cited
2000
Molecular portraits of human breast tumours
Human breast tumours are diverse in their natural history and in their responsiveness to treatments. Variation in transcriptional… (More)
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Highly Cited
1998
Highly Cited
1998
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
Rap1 is a small, Ras-like GTPase that was first identified as a protein that could suppress the oncogenic transformation of cells… (More)
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Highly Cited
1998
Highly Cited
1998
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13.
Signaling pathways that link extracellular factors to activation of the monomeric guanosine triphosphatase (GTPase) Rho control… (More)
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Highly Cited
1993
Highly Cited
1993
Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.
A human complementary DNA was isolated that encodes a widely expressed protein, hSos1, that is closely related to Sos, the… (More)
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Highly Cited
1992
Highly Cited
1992
Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein
THE fungal metabolite brefeldin A is a powerful tool for investigating membrane traffic in eukaryotic cells1. The effects of… (More)
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Highly Cited
1991
Highly Cited
1991
Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase
We have conducted a genetic screen for mutations that decrease the effectiveness of signaling by a protein tyrosine kinase, the… (More)
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Highly Cited
1984
Highly Cited
1984
Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.
Membranes from bovine brain bind relatively large quantities of guanosine 5'-(3-O-thio)triphosphate (GTP gamma S) with high… (More)
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