Nomenclature of Voltage-Gated Calcium Channels
- E. A. Ertel, K. Campbell, W. Catterall
- BiologyNeuron
- 1 March 2000
Functional interaction between InsP3 receptors and store-operated Htrp3 channels
- K. Kiselyov, Xin Xu, S. Muallem
- BiologyNature
- 3 December 1998
It is shown that Htrp3 channels stably expressed in HEK293 cells are in a tight functional interaction with the InsP3 receptors, providing evidence for the coupling hypothesis, in which InsP 3 receptors activated by InsP2 interact with SOC and regulate Icrac.
The TRP Channels, a Remarkably Functional Family
- C. Montell, L. Birnbaumer, V. Flockerzi
- Biology, PsychologyCell
- 8 March 2002
Increased Vascular Smooth Muscle Contractility in TRPC6−/− Mice
- A. Dietrich, M. Mederos y Schnitzler, L. Birnbaumer
- BiologyMolecular and Cellular Biology
- 15 August 2005
It is implied that constitutively active TRPC3-type channels, which are up-regulated in TRPC6-deficient smooth muscle cells, are not able to functionally replace TRPC 6, which has distinct nonredundant roles in the control of vascular smooth muscle tone.
Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channels.
- H. Ma, R. Patterson, D. V. van Rossum, L. Birnbaumer, K. Mikoshiba, D. Gill
- BiologyScience
- 3 March 2000
It is concluded that insP3Rs mediate both SOC and TRP channel opening and that the InsP3R is essential for maintaining coupling between store emptying and physiological activation of SOCs.
trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry
- Xi Zhu, M. Jiang, L. Birnbaumer
- BiologyCell
- 31 May 1996
TRPC3 Channels Are Required for Synaptic Transmission and Motor Coordination
- J. Hartmann, E. Dragicevic, A. Konnerth
- BiologyNeuron
- 14 August 2008
Receptor-effector coupling by G proteins.
- L. Birnbaumer, J. Abramowitz, A. Brown
- BiologyBiochimica et Biophysica Acta
- 7 May 1990
Orai proteins interact with TRPC channels and confer responsiveness to store depletion
- Yanhong Liao, C. Erxleben, E. Yildirim, J. Abramowitz, D. Armstrong, L. Birnbaumer
- BiologyProceedings of the National Academy of Sciences
- 13 March 2007
It is proposed that Orai proteins by interacting with TRPCs act as regulatory subunits that confer STIM1-mediated store depletion sensitivity to these channels.
Identification of Common Binding Sites for Calmodulin and Inositol 1,4,5-Trisphosphate Receptors on the Carboxyl Termini of Trp Channels*
- Jisen Tang, Yakang Lin, Zongming Zhang, S. Tikunova, L. Birnbaumer, M. Zhu
- Biology, ChemistryJournal of Biological Chemistry
- 15 June 2001
The data support the view that both CaM and IP3Rs play important roles in controlling the gating of Trp-based channels, however, the sensitivity and responses toCaM andIP3Rs differ for each Trp.
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