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6-thioguanylic acid

Known as: 6-thioguanine nucleotide, 6-thioguanosine-5'-phosphate, 6-thioguanosine monophosphate 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Guanine NucleotidesThionucleotides

Papers overview

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2011
2011
The Role of Inosine-5′-Monophosphate Dehydrogenase in Thiopurine Metabolism in Patients With Inflammatory Bowel Disease
Background: There is a large interindividual variability in thiopurine metabolism. High concentrations of methylthioinosine-5… 
2008
2008
Thiopurine methyltransferase activity combined with 6-thioguanine metabolite levels predicts clinical response to thiopurines in patients with inflammatory bowel disease.
1997
1997
Pharmacokinetics and distribution of 6-mercaptopurine administered intravenously in children with lymphoblastic leukaemia
AbstractObjective: The pharmacokinetics of 6-mercaptopurine, including cerebrospinal-fluid (CSF) distribution, and the… 
1997
1997
Pharmacokinetics of mercaptopurine: plasma drug and red cell metabolite concentrations after an oral dose.
Measurement of red cell 6-mercaptopurine (MP) derived 6-thioguanine nucleotide (TGN) and methylmercaptopurine metabolites (MeMPs… 
1994
1994
MONITORING OF AZATHIOPRINE TREATMENT BY DETERMINATION OF 6‐THIOGUANINE NUCLEOTIDE CONCENTRATIONS IN ERYTHROCYTES1
Thioguanine nucleotides (6-TGN) are intracellular metabolites that may contribute to the antiproliferative effects of AZA. The… 
1993
1993
6-Thioguanine nucleotide accumulation in erythrocytes during azathioprine treatment for systemic connective tissue diseases: a possible index for monitoring treatment.
BACKGROUND: Owing to adverse pharmacokinetics, azathioprine treatment may fail to induce a satisfactory clinical response in… 
1985
1985
Conversion of 6-mercaptopurine to 6-thioguanylic acid in L-1210 cells and human leukemia cells.
The metabolism of 6-mercaptopurine (6-MP) in L-1210 mouse leukemia cells and human chronic myelocytic leukemia cells (CML cells… 
1984
1984
Severe megaloblastic anaemia associated with abnormal azathioprine metabolism.
Severe anaemia is a rare, unexplained, side effect of azathioprine therapy. We report here such a case associated with a… 
1978
1978
The quantitative determination of metabolites of 6-mercaptopurine in biological materials. III. The determination of 14C-labeled 6-thiopurines in L5178Y cell extracts using high-pressure liquid…
1975
1975
Quantitation of contact-feeding between somatic cells in culture.
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