6-thioguanylic acid

Known as: 6-thioguanine nucleotide, 6-thioguanosine-5'-phosphate, 6-thioguanosine monophosphate 
 
National Institutes of Health

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2006
2006
BACKGROUND Small uncontrolled trials have suggested that 5-aminosalicylate (5-ASA) medications increase 6-thioguanine nucleotide… (More)
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Highly Cited
2004
Highly Cited
2004
Proper prospective pharmacokinetic studies of 6-mercaptopurine (6-MP) in inflammatory bowel disease (IBD) patients are lacking… (More)
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2003
2003
BACKGROUND Measurement of 6-thioguanine nucleotide (6-TGN) concentrations in erythrocytes is widely accepted for use in… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND & AIMS Approximately 40% of inflammatory bowel disease (IBD) patients fail to benefit from 6-mercaptopurine (6-MP… (More)
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Highly Cited
2001
Highly Cited
2001
AIM We evaluated the effect of coadministration of sulphasalazine, mesalamine, and balsalazide on the pharmacokinetics and… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Measurement of 6-thioguanine nucleotide concentrations may be useful for optimising treatment with azathioprine and 6… (More)
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Highly Cited
1991
Highly Cited
1991
Thiopurine methyltransferase deficiency, inherited as an autosomal codominant trait, is associated with aberrant mercaptopurine… (More)
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Highly Cited
1987
Highly Cited
1987
Thiopurine methyltransferase (TPMT) catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (6-MP) and… (More)
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Highly Cited
1983
Highly Cited
1983
6-Mercaptopurine is extensively used in the treatment of childhood lymphoblastic leukaemia to prolong the duration of remission… (More)
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Highly Cited
1975
Highly Cited
1975
The effects of 6-thioguanine on purine biosynthesis and cell viability have been examined in H.Ep. 2 cells grown in culture… (More)
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