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Genes, Immunoglobulin
Known as:
Ig Gene
, Genes, Ig
, Gene, Immunoglobulin
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Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN…
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National Institutes of Health
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Related topics
Related topics
15 relations
Gene Rearrangement
Immunogenetics
Immunoglobulin Allotypes
Immunoglobulin Class Switching
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Narrower (2)
IGH gene
variable region gene
Broader (1)
Structural gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Nuclear factors bind to regulatory regions of the mouse kappa immunoglobulin gene.
R. Hromas
,
B. V. Van Ness
Nucleic Acids Research
1986
Corpus ID: 31076574
At least two regions of the mouse kappa immunoglobulin gene are necessary for appropriate transcription. One is located within…
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Review
1985
Review
1985
NIH conference. Molecular genetic analysis of human lymphoid neoplasms. Immunoglobulin genes and the c-myc oncogene.
Thomas A. Waldmann
,
S. Korsmeyer
,
A. Bakhshi
,
A. Arnold
,
Ilan R. Kirsch
Annals of Internal Medicine
1985
Corpus ID: 2200183
Immunoglobulin genes responsible for individual antibodies are organized as discontinuous DNA segments in their germline form. As…
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Highly Cited
1984
Highly Cited
1984
DNA rearrangements of immunoglobulin genes correlate with phenotypic markers in B-cell malignancies.
L. Foroni
,
D. Catovsky
,
T. Rabbitts
,
L. Luzzatto
Molecular biology & medicine
1984
Corpus ID: 44953382
We have investigated the configuration of immunoglobulin (Ig) genes in leukaemic cells in 17 patients with B-cell leukaemias (11…
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Review
1983
Review
1983
Biosynthesis and regulation of immunoglobulins.
R. Wall
,
M. Kuehl
Annual Review of Immunology
1983
Corpus ID: 27884140
Immunoglobulin gene expression exhibits a number of intriguing regulatory features. Immunoglobulin genes undergo dynamic DNA…
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1982
1982
Relationship between the rearrangement of immunoglobulin genes, the appearance of a B lymphocyte antigen, and immunoglobulin synthesis in murine pre-B cell lines.
H. Sugiyama
,
S. Akira
,
+5 authors
T. Kishimoto
Journal of Immunology
1982
Corpus ID: 22833472
Eighteen Abelson virus-transformed immature B cell lines were established and immunoglobulin biosynthesis, expression of a B…
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1980
1980
The variability, arrangement, and rearrangement of immunoglobulin genes.
T. Rabbitts
,
P. Hamlyn
,
G. Matthyssens
,
B. Roe
Canadian Journal of Biochemistry
1980
Corpus ID: 37462316
The multiplicity of heavy-chain variable-region (VH) genes in mouse and human DNA has been estimated using a mouse heavy-(H…
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1979
1979
Split immunoglobulin genes and human heavy chain deletion-mutants.
Blas Frangione
,
E. C. Franklin
Journal of Immunology
1979
Corpus ID: 42354394
In 1965, the “two gene-one polypeptide” theory for the synthesis of antibody chains was first proposed (1). Since then, amino…
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1979
1979
Human heavy chain disease protein WIS: implications for the organization of immunoglobulin genes.
E. Franklin
,
F. Prelli
,
B. Frangione
Proceedings of the National Academy of Sciences…
1979
Corpus ID: 37663149
Protein WIS is a human gamma3 heavy (H) chain disease immunoglobulin variant whose amino acid sequence is most readily…
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1974
1974
The organization and diversity of immunoglobulin genes.
P. Leder
,
T. Honjo
,
S. Packman
,
D. Swan
,
M. Nau
,
B. Norman
Proceedings of the National Academy of Sciences…
1974
Corpus ID: 9725202
We have used purified mouse immunoglobulin light chain mRNA and synthetic DNA which is complementary to it to assess the…
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1972
1972
Quantitation of immunoglobulin genes by nucleic acid hybridization with RNA from myeloma and spleen microsomes.
U. Storb
Journal of Immunology
1972
Corpus ID: 39584842
Nucleic acid hybridization has been used in an attempt to determine the fraction of spleen DNA which is homologous to…
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