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IGH gene

Known as: Immunoglobulin Heavy Locus, Immunoglobulin Heavy Chain Genes, Immunoglobulin Heavy Chain Locus 
This region represents the germline organization of the immunoglobulin heavy chain locus. The locus includes V (variable), J (joining), diversity (D… 
National Institutes of Health

Related topics

Related topics

9 relations
14q32.33Humoral ImmunityImmune responseImmunoglobulin Gm Allotypes

Broader (1)

Genes, Immunoglobulin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
IGH and IGK gene rearrangements as PCR targets for pediatric Burkitt's lymphoma and mature B-ALL MRD analysis
We recently reported that minimal residual disease (MRD) and minimal disseminated disease (MDD), assessed by long-distance PCR… 
2006
2006
Mutated or non-mutated? Which database to choose when determining the IgVH hypermutation status in chronic lymphocytic leukemia?
It has been accepted that the hypermutation status of immunoglobulin heavy chain genes (IgVH) is one of the most important… 
1999
1999
Opposite orientation of the α- and υ-chain constant region genes in the immunoglobulin heavy chain locus of the duck
1998
1998
Autoreactive B cell clones in marginal-zone B cell lymphoma (MALT lymphoma) of the stomach
The onset of mucosa-associated lymphoid tissue (MALT) lymphomas in the stomach is preceded by the acquisition of MALT as a result… 
1991
1991
Absence of t(14;18) major and minor breakpoints and of Bcl-2 protein overproduction in Reed-Sternberg cells of Hodgkin's disease.
The t(14;18) translocation, found in most human follicular non-Hodgkin's lymphomas (NHLs), juxtaposes the Bcl-2 oncogene at 18q21… 
1986
1986
High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene.
The "silent" allele at the immunoglobulin heavy-chain locus in the pre-B-lymphocyte line 18-81 contains a correctly assembled… 
1986
1986
Identification of a genetic locus, Rsm-1, controlling protective immunity against Schistosoma mansoni.
Mice of most inbred strains develop moderate to high levels of resistance to challenge infection on vaccination with radiation… 
1986
1986
Polymorphism and evolution of Igh-V gene families.
The immunoglobulin heavy chain locus (Igh) is located on chromosome 12 of the mouse. It is a complex locus, containing over one… 
1985
1985
Human T-cell receptor alpha-chain genes: location on chromosome 14.
The genes encoding the alpha chain of the human T-cell receptor have been mapped to chromosome 14, the chromosome on which the… 
1984
1984
Establishment and functional analysis of a cloned, antigen-specific suppressor effector T cell line.
A long-term cultured suppressor T cell line (3D10) was established from the spleen cells of KLH hyperimmunized C3H mice. The… 
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