IGH gene

Known as: Immunoglobulin Heavy Locus, Immunoglobulin Heavy Chain Genes, Immunoglobulin Heavy Chain Locus 
This region represents the germline organization of the immunoglobulin heavy chain locus. The locus includes V (variable), J (joining), diversity (D… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Immunoglobulin variable region exons are assembled in developing B cells by V(D)J recombination. Once mature, these cells undergo… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Chromosomal translocations involving the immunoglobulin switch region are a hallmark feature of B-cell malignancies. However… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The three chromosomal translocations t(11;18)(q21;q21), t(14;18)(q32;q21), and t(1;14)(p22;q32) are associated with MALT lymphoma… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Polycomb group protein Ezh2 is an essential epigenetic regulator of embryonic development in mice, but its role in the adult… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Review
2003
Review
2003
In a European BIOMED-2 collaborative study, multiplex PCR assays have successfully been developed and standardized for the… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Amplification of large genomic regions associated with complex translocations (complicons) is a basis for tumor progression and… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Large-scale clinical studies on detection of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) have shown that… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The Pax5 gene coding for the transcription factor BSAP has an essential role in B lymphopoiesis and midbrain development. Here we… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
We have employed a method based on the Cre-loxP recombination system of bacteriophage P1 to generate a mouse strain in which the… (More)
Is this relevant?
Highly Cited
1982
Highly Cited
1982
The consistent appearance of specific chromosomal translocations in human Burkitt lymphomas and murine plasmacytomas has… (More)
Is this relevant?