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GPR158 gene

Known as: G protein-coupled receptor 158, G Protein-Coupled Receptor 158 Gene, KIAA1136 
This gene plays a role in the mediation of G protein-coupled receptor signaling.
National Institutes of Health

Related topics

Related topics

6 relations
G Protein-Coupled Receptor SignalingGPR15 geneLigand BindingProbable G-Protein Coupled Receptor 158, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas
Ovarian cancer is the main cause of gynecological cancer-associated death. However, 5-year survival rates differ dramatically… 
2018
2018
Homeostatic cAMP regulation by the RGS7 complex controls depression-related behaviors
Affective disorders arise from abnormal responses of the brain to prolonged exposure to challenging environmental stimuli. Recent… 
2018
2018
Orphan receptor GPR158 controls stress-induced depression
Stress can be a motivational force for decisive action and adapting to novel environment; whereas, exposure to chronic stress… 
2018
2018
Inhibitory Signaling to Ion Channels in Hippocampal Neurons Is Differentially Regulated by Alternative Macromolecular Complexes of RGS7
The neuromodulatory effects of GABA on pyramidal neurons are mediated by GABAB receptors (GABABRs) that signal via a conserved G… 
2017
2017
A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians
Pima Indians living in Arizona have a high prevalence of obesity, and we have previously shown that a relatively lower energy… 
Highly Cited
2015
Highly Cited
2015
Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain*♦
Background: RGS7 plays an essential role in regulating neuronal G protein signaling. Results: Elimination of GPR158 in mice… 
2015
2015
Expression and Functional Role of Orphan Receptor GPR158 in Prostate Cancer Growth and Progression
Prostate cancer (PCa) is the second-leading cause of cancer-related mortality, after lung cancer, in men from developed countries… 
2013
2013
GPR158, an Orphan Member of G Protein-Coupled Receptor Family C: Glucocorticoid-Stimulated Expression and Novel Nuclear Role
Members of the large G protein-coupled receptor (GPCR) clan are implicated in many physiological and disease processes, making… 
Highly Cited
2012
Highly Cited
2012
Genome-wide association study of antibody response to smallpox vaccine.
Review
2005
Review
2005
The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors.
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