• Publications
  • Influence
Score tests for association between traits and haplotypes when linkage phase is ambiguous.
A key step toward the discovery of a gene related to a trait is the finding of an association between the trait and one or more haplotypes. Haplotype analyses can also provide critical informationExpand
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Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics
Two recently developed fine-mapping methods, CAVIAR and PAINTOR, demonstrate better performance over other fine-mapping methods. They also have the advantage of using only the marginal testExpand
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3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer
BackgroundMassive parallel sequencing has the potential to replace microarrays as the method for transcriptome profiling. Currently there are two protocols: full-length RNA sequencing (RNA-SEQ) andExpand
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Making vaccines more acceptable--methods to prevent and minimize pain and other common adverse events associated with vaccines.
The growing abundance of highly immunogenic vaccines has arrived with a burden of pain, distress, and common adverse reactions that in turn may interfere with parental compliance and aggravateExpand
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Value of Immunological Markers in Predicting Responsiveness to Influenza Vaccination in Elderly Individuals
ABSTRACT Elderly individuals are at high risk for morbidity and mortality when infected with influenza virus. Vaccinations with inactivated virus are less effective in the elderly due to theExpand
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Requiring influenza vaccination for health care workers: seven truths we must accept.
In this paper we outline the seven primary truths supporting the call for requiring influenza immunization of all health care workers. We view this as a serious patient safety issue, given the clearExpand
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Calculating Sample Size Estimates for RNA Sequencing Data
TLDR
We derive an explicit sample size formula which includes both sequence based counting and biological variability, while avoiding the rapidly diminishing returns (and expense) of over-increasing sequencing depth. Expand
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Live attenuated measles virus induces regression of human lymphoma xenografts in immunodeficient mice.
Derivatives of the Edmonston-B strain of measles virus (MV-Ed) are safe, live attenuated measles virus (MV) vaccines that have been used worldwide for more than 30 years. The cytoreductive potentialExpand
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Revised SHEA position paper: influenza vaccination of healthcare personnel.
  • T. Talbot, H. Babcock, +6 authors David J Weber
  • Medicine
  • Infection control and hospital epidemiology
  • 1 October 2010
Executive Summary This document serves as an update and companion piece to the 2005 Society for Healthcare Epidemiology of America (SHEA) Position Paper entitled “Influenza Vaccination of HealthcareExpand
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Heterogeneity in Vaccine Immune Response: The Role of Immunogenetics and the Emerging Field of Vaccinomics
Recent advances in the fields of immunology, genetics, molecular biology, bioinformatics, and the Human Genome Project have allowed for the emergence of the field of vaccinomics. VaccinomicsExpand
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