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GABA Antagonists

Known as: Antagonists, GABA, Acid Antagonists, gamma-Aminobutyric, gamma Aminobutyric Acid Antagonists 
Drugs that bind to but do not activate GABA RECEPTORS, thereby blocking the actions of endogenous GAMMA-AMINOBUTYRIC ACID and GABA RECEPTOR AGONISTS.
National Institutes of Health

Related topics

Related topics

22 relations

Narrower (16)

5-hydroxysaclofenAllylglycineBicucullineCGP 35348

Broader (1)

Alkaloids
In Bloodaspects of radiation effectschemical synthesisgamma-Aminobutyric Acid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Effects of GABAergic drugs on the GABA turnover in the substantia nigra and the corpus striatum of the rat
Changes in the endogenous GABA concentration and in GABA turnover following GABA receptor stimulation or blockade were studied in… 
2004
2004
Effect of GABA antagonist-induced seizures on3H-muscimol and3H-diazepam binding in the rat striatum
The binding of 3H-muscimol and 3H-diazepam to rat striatum membranes after picrotoxin- and bicuculline-induced seizures was… 
1997
1997
Square-wave jerks and square-wave oscillations: treatment with valproic acid
Experimental studies in monkeys have demonstrated that injection of gamma-aminobutyric acid (GABA) agonists into the superior… 
1986
1986
Benzodiazepines inhibit thyrotropin (TSH)-releasing hormone-induced TSH and growth hormone release from perifused rat pituitaries.
The perifusion technique was used to investigate the action of diazepam (DZ), a benzodiazepine molecule known to compete for TRH… 
1986
1986
Lack of involvement of GABA in baroreceptor-mediated sympathoinhibition.
The purpose of the present investigation was to determine if gamma-aminobutyric acid (GABA) mediates the baroreceptor-induced… 
1986
1986
GABA antagonists increase the release of [3H]acetylcholine from the chick retina.
The release of [3H]acetylcholine from the chick retina was studied. A 5 mM increase in K+-concentration caused an increased… 
1983
1983
Suppression of a Somatosympathetic Reflex by the γ-Aminobutyric Acid Agonist Muscimol and by Clonidine
Summary γ-Aminobutyric acid (GABA) and GABA agonists, e.g., muscimol, reduce blood pressure and sympathetic outflow and inhibit… 
1982
1982
Role of globus pallidus GABA and opiate receptors in apomorphine circling in nigro-striatal lesioned rats
SummaryThe effect of lesioning the ipsilateral globus pallidus (GP) on apomorphine-induced circling in nigrostriatal lesioned… 
1980
1980
Two distinct inhibitory responses of cultured, mammalian spinal neurones to ibotenic acid.
Ibotenic acid, a structural analogue of glutamic acid, was applied to mouse spinal neurones grown in dissociated cultures. This… 
1979
1979
Hypersynchronisation and sedation produced by GABA-transaminase inhibitors and picrotoxin: does GABA participate in sleep control?
Systemic administration of GABA-transaminase inhibitors, gamma-acetylenic GABA (100 mg/kg) or gamma-vanylic GABA (1200 mg/kg… 
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