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Allylglycine

Known as: 2-Amino-4-Pentenoic Acid, 4-Pentenoic acid, 2-amino-, Allylglycine [Chemical/Ingredient] 
An inhibitor of glutamate decarboxylase and an antagonist of GAMMA-AMINOBUTYRIC ACID. It is used to induce convulsions in experimental animals.
National Institutes of Health

Related topics

Related topics

9 relations

Broader (2)

ConvulsantsGABA Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Stereocontrolled routes to beta,beta'-disubstituted alpha-amino acids.
Owing to their significant abundance in natural products, chiral beta,beta'-disubstituted alpha-amino acids remain an important… 
Highly Cited
1984
Highly Cited
1984
Changes in Regional Neurotransmitter Amino Acid Levels in Rat Brain During Seizures Induced by l‐Allylglycine, Bicuculline, and Kainic Acid
Abstract: Changes in amino acid concentrations were studied in the cortex, cerebellum, and hippocampus of the rat brain, after 20… 
Highly Cited
1983
Highly Cited
1983
EARLY CHANGES IN THE RAT HIPPOCAMPUS FOLLOWING SEIZURES INDUCED BY BICUCULLINE OR L‐ALLYLGLYCINE: A LIGHT AND ELECTRON MICROSCOPE STUDY
Evans M, Griffiths T & Meldrum B (1983) Neuropathology and Applied Neurobiology 9, 39–52 
1981
1981
Cortical unit activity during intermittent photic stimulation in Papio papio. Relationship with paroxysmal fronto-rolandic activity.
Highly Cited
1981
Highly Cited
1981
Involvement of the GABAergic System on Shock-induced Aggressive Behavior in Two Strains of Mice
1980
1980
Paroxysmal visual evoked potentials (PVEPs) in Papio papio. I. Morphological and topographical characteristics. Comparison with paroxysmal discharges.
Highly Cited
1979
Highly Cited
1979
Effects of some anti-epileptic, neuroleptic and gabaminergic drugs on convulsions induced by D,L-allyglycine
1979
1979
Effects of opiate-like peptides, morphine, and naloxone in the photosensitive baboon, papio papio
1975
1975
Chemically induced choreiform activity: Antagonism by GABA and EEG patterns
1974
1974
SOME PROPERTIES OF GUINEA PIG BRAIN GLUTAMATE DECARBOXYLASE AND ITS INHIBITION BY THE CONVULSANT ALLYLGLYCINE (2‐AMINO‐4‐PENTENOIC ACID) 1
—Glutamate decarboxylase (l‐glutamate 1‐carboxy‐lyase EC 4.1.1.15; GAD) has been isolated from guinea pig brain and some of its… 
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