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Bicuculline

Known as: 6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)furo(3,4-e)1,3-benzodioxol-8(6H)one, Bicuculline [Chemical/Ingredient], Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,S*))- 
An isoquinoline alkaloid obtained from Dicentra cucullaria and other plants. It is a competitive antagonist for GABA-A receptors.
National Institutes of Health

Related topics

Related topics

17 relations

Broader (6)

AlkaloidsAnalepticsConvulsantsGABA Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (4)

bicuculline methiodidebicuculline methobromidebicuculline methochloridebicuculline methoxide

Papers overview

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2004
2004
Antiviral and Antiplasmodial Spirodihydrobenzofuran Terpenes from the Fungus Stachybotrys nephrospora
1 2 Stachybotrys nephrospora 1 2 1 2 1 2 1 2 
1994
1994
Spinodal decomposition of Fe-Cu nanocrystals: Control of atomic-magnetic-moment and magnetic properties.
Experimental results corresponding to the saturation magnetization and coercive field during the decomposition, upon annealing… 
1993
1993
Magnetization of ultrathin bcc Fe films on MgO.
  • HuangLiuFelcher
  • Physical Review B (Condensed Matter)
  • 1993
  • Corpus ID: 38432517
The magnetization of body-centered-cubic iron was measured by means of polarized neutron reflection on a set of films of… 
1993
1993
Pulsed laser evaporation of boron/carbon pellets: Infrared spectra and quantum chemical structures and frequencies for BC2
Pulsed laser evaporation of pellets pressed from boron and graphite powder gave a new 1:4 doublet at 1232.5 and 1194.6 cm−1 in… 
1993
1993
Microscopic theory of the martensitic transition in Fe1-xNix.
Fixed-spin-moment band-structure calculations of ${\mathrm{Fe}}_{3}$Ni show that the face-centered-cubic structure is unstable… 
1992
1992
X-ray analysis of changes to the atomic structure around Ni associated with the interdiffusion and mechanical alloying of pure Ni and Mo powders.
We have applied a combination of x-ray diffraction and x-ray-absorption spectroscopy to probe, in a self-consistent way, the bulk… 
Highly Cited
1989
Highly Cited
1989
Direct experimental identification of the structure of ultrathin films of bcc iron and metastable bcc and fcc cobalt.
  • LiTonner
  • Physical Review B (Condensed Matter)
  • 1989
  • Corpus ID: 21858117
X-ray-excited photoemission and Auger-electron angular distributions from epitaxial transition-metal films are shown to be… 
1989
1989
Magnetic anisotropy of Gd(0001)/W(110) monolayers.
The uniaxial magnetic anisotropy of Gd(0001) monolayers and of an 80-A\r{} epitaxial film on W(110) is determined near ${T}_{c… 
1985
1985
Individual collision cascades in static bcc polycrystals.
  • Hou
  • Physical Review B (Condensed Matter)
  • 1985
  • Corpus ID: 24133567
Highly Cited
1979
Highly Cited
1979
Effects of bicuculline‐induced seizures on cerebral metabolism and circulation of rats rendered hypoglycemic by starvation
To evaluate the effects of substrate deficiency on cerebral function, metabolism, and blood flow during seizures, rats were…