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Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models
Effects of intracerebroventircular (ICV), neuropeptide Y (NPY) (0.2–5.0 nmol) and its C-terminal 13–36 amino acid (AA) fragment (0.4–2.0 nmol) have been examined with respect to anxiolytic propertiesExpand
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The Glucagon-Like Peptide 1 Analogue, Exendin-4, Attenuates the Rewarding Properties of Psychostimulant Drugs in Mice
Glucagon-like peptide 1 (GLP-1) is an incretine hormone that controls consummatory behavior and glucose homeostasis. It is released in response to nutrient ingestion from the intestine and productionExpand
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Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points.
Male rhesus monkeys (Macaca mulatta) of different age groups representing the species life span were fed ad libitum or a 30% reduced calorie diet over a 7-yr period. During the first 2-3 yr of thisExpand
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Role of dopamine in prepulse inhibition of acoustic startle
Abstract Rationale: Prepulse inhibition of acoustic startle is the reduction in startle response to an intense auditory stimulus when this stimulus is immediately preceded by a weaker prestimulus.Expand
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The glucagon-like peptide 1 analogue Exendin-4 attenuates alcohol mediated behaviors in rodents
Development of alcohol use disorders largely depends on the effects of alcohol on the brain reward systems. Emerging evidence indicate that common mechanisms regulate food and alcohol intake andExpand
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Ghrelin receptor antagonism attenuates cocaine- and amphetamine-induced locomotor stimulation, accumbal dopamine release, and conditioned place preference
IntroductionRecently we demonstrated that genetic or pharmacological suppression of the central ghrelin signaling system, involving the growth hormone secretagogue receptor 1A (GHS-R1A), lead to aExpand
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Anxiolytic-like action of centrally administered galanin
The neuropeptide galanin is present in limbic brain areas important for emotionality. We examined whether central galanin may be involved in mechanisms of anxiety. Rats were tested in aExpand
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Effects of subunit selective nACh receptors on operant ethanol self-administration and relapse-like ethanol-drinking behavior
Rationale and objectivesThe sensitivity to ethanol central effects is partially determined by the subunit composition of brain nicotinic acetylcholine receptors (nAChRs). Thus, the effects ofExpand
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Effects of GABAergic agonists and antagonists on various ethanol-induced behavioral changes
The interaction between ethanol and various GABAergic drugs (muscimol, bicuculline, picrotoxin) with regard to their effects on locomotor activity, drug-induced sleep, body temperature, andExpand
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The Ghrelin Signalling System Is Involved in the Consumption of Sweets
The gastric-derived orexigenic peptide ghrelin affects brain circuits involved in energy balance as well as in reward. Indeed, ghrelin activates an important reward circuit involved in natural- asExpand
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