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Ficusin

Known as: Psoralene, Psoralen, Ficusin [Chemical/Ingredient] 
A furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division. Psoralen is used in Photochemotherapy with high-intensity long… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (5)

5-(3-Phenylpropoxy)psoralen5-(4-phenylbutoxy)psoralenS-59, psoralenalpha-methylene-gamma-butyrolactone-psoralen

Broader (3)

AnthelminticsCross-Linking ReagentsPhotosensitizing Agents
FurocoumarinsIn BloodMethoxsalenPsoralen [EPC]

Papers overview

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Highly Cited
2009
Highly Cited
2009
Chitosan based oligoamine polymers: synthesis, characterization, and gene delivery.
Highly Cited
1999
Highly Cited
1999
Induction of Epstein-Barr virus-specific cytotoxic T-lymphocyte responses using dendritic cells pulsed with EBNA-3A peptides or UV-inactivated, recombinant EBNA-3A vaccinia virus.
Cell-mediated immunity, especially the cytotoxic T lymphocyte (CTL), provides resistance to Epstein-Barr virus (EBV), as is… 
Highly Cited
1989
Highly Cited
1989
Site specificity of the inhibitory effects of oligo(nucleoside methylphosphonate)s complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4.
Oligo(nucleoside methylphosphonate)s complementary to the splice junction of herpes simplex virus type 1 immediate early pre… 
Highly Cited
1985
Highly Cited
1985
Localization of a base-paired interaction between small nuclear RNAs U4 and U6 in intact U4/U6 ribonucleoprotein particles by psoralen cross-linking.
Highly Cited
1985
Highly Cited
1985
A possible mechanism of psoralen phototoxicity not involving direct interaction with DNA.
Psoralens in combination with ultraviolet light (UVA; 320-400 nm) are used in the photochemical treatment of a variety of skin… 
Review
1984
Review
1984
The reaction of the psoralens with deoxyribonucleic acid
Psoralen photochemistry is specific for nucleic acids and is better understood at the molecular level than are all other methods… 
Highly Cited
1983
Highly Cited
1983
Differential response of cultured parsley cells to elicitors from two non-pathogenic strains of fungi. 1. Identification of induced products as coumarin derivatives.
Dark-grown cell suspension cultures of parsley, Petroselinum hortense, produce furanocoumarins after treatment with elicitor… 
Highly Cited
1982
Highly Cited
1982
Genetic control of excision of Saccharomyces cerevisiae interstrand DNA cross-links induced by psoralen plus near-UV light
Excision of interstrand DNA cross-links induced by 4,5',8-trimethyl psoralen plus 360-nm light was examined in wild type (RAD… 
Highly Cited
1978
Highly Cited
1978
Oral psoralen photochemotherapy of atopic eczema
Oral administration of 8‐methoxypsoralen followed by exposure to a high‐intensity longwave ultraviolet treatment system resulted… 
Highly Cited
1973
Highly Cited
1973
Psoralen plus black light inhibits epidermal DNA synthesis.
Psoralens have been used previously in an attempt to repigment vitiliginous skin. Recent reports indicate psoralens, activated by… 
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