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Ficusin

Known as: Psoralene, Psoralen, Ficusin [Chemical/Ingredient] 
A furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division. Psoralen is used in Photochemotherapy with high-intensity long… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (5)

5-(3-Phenylpropoxy)psoralen5-(4-phenylbutoxy)psoralenS-59, psoralenalpha-methylene-gamma-butyrolactone-psoralen

Broader (3)

AnthelminticsCross-Linking ReagentsPhotosensitizing Agents
FurocoumarinsIn BloodMethoxsalenPsoralen [EPC]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Guideline for the diagnosis and management of vitiligo
This detailed and user‐friendly guideline for the diagnosis and management of vitiligo in children and adults aims to give high… 
Highly Cited
2002
Highly Cited
2002
RNAi in human cells: basic structural and functional features of small interfering RNA.
Highly Cited
2000
Highly Cited
2000
Repair of an Interstrand DNA Cross-link Initiated by ERCC1-XPF Repair/Recombination Nuclease*
Interstrand DNA cross-link damage is a severe challenge to genomic integrity. Nucleotide excision repair plays some role in the… 
Highly Cited
1997
Highly Cited
1997
Treatment of vitiligo with UV-B radiation vs topical psoralen plus UV-A.
OBJECTIVE To compare the efficacy and safety of 2 treatment modalities, topical psoralen plus UV-A (PUVA) with unsubstituted… 
Highly Cited
1997
Highly Cited
1997
Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long‐wavelength ultraviolet light
BACKGROUND: A photochemical treatment process has been developed for the inactivation of viruses and bacteria in platelet… 
Highly Cited
1993
Highly Cited
1993
Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae.
The chromatin structure of yeast ribosomal DNA was analyzed in vivo by crosslinking intact cells with psoralen. We found that in… 
Highly Cited
1989
Highly Cited
1989
Two different chromatin structures coexist in ribosomal RNA genes throughout the cell cycle
Highly Cited
1982
Highly Cited
1982
The Science of Photomedicine
presented at the 7th Annual Meeting of the American Society for Photobiology, June 24-28, Pacific Grove, California. Programs and… 
Highly Cited
1973
Highly Cited
1973
Repair of DNA containing interstrand crosslinks in Escherichia coli: sequential excision and recombination.
The repair of DNA containing interstrand crosslinks induced by psoralen-plus-light in E. coli cells has been investigated. During… 
Highly Cited
1970
Highly Cited
1970
Light-induced cross-linking of DNA in the presence of a furocoumarin (psoralen). Studies with phage lambda, Escherichia coli, and mouse leukemia cells.
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