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Methoxsalen

Known as: 6-Hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone, 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, O-Methylxanthotoxol 
A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of… 
National Institutes of Health

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3,4'-dimethyl-8-methoxypsoralen4-bromo-8-methoxypsoralen5-hydroxy-8-methoxypsoralen5-methoxypsoralen
AlbinismAphakiaCataractChild

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Cross-Linking Reagents

Papers overview

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1982
1982
Sister chromatid exchange induced by short-lived monoadducts produced by the bifunctional agents mitomycin C and 8-methoxypsoralen.
To see if DNA crosslinks are involved in the induction of sister chromatid exchange (SCE), Chinese hamster ovary cells were… 
1982
1982
Psoralen--long-wave ultraviolet therapy and human cataractogenesis.
Cataract formation associated with psoralen--long-wave ultraviolet (P-UVA) therapy has been documented in experimental animals… 
Review
1980
Review
1980
Drug-resistant lymphocytes in man as indicators of somatic cell mutation.
Direct in vivo tests of somatic mutation in man may provide realism in assessing the genetic risks of potential environmental… 
1980
1980
Absence of cataract ten years after treatment with 8-methoxypsoralen.
Thirteen patients treated with 4-41 g of 8-methoxypsoralen (8-MOP) for vitiligo were examined with regard to ocular damage 2-12… 
Highly Cited
1978
Highly Cited
1978
Characterization of sister chromatid exchange induction by 8-methoxypsoralen plus near UV light.
The combination of 8-methoxypsoralen and near UV light is highly effective in inducing sister chromatid exchanges (SCEs) in… 
Highly Cited
1978
Highly Cited
1978
Psoralen-UVA-treated psoriatic lesions. Ultrastructural changes.
Psoralen-ultraviolet light (PUVA)-treated psoriatic lesions were studied for ultrastructural changes. In early stages of… 
1978
1978
Serum levels of 8-methoxypsoralen 2 hours after oral administration.
Serum levels of 8-methoxypsoralen (8-MOP) were determined 2 hours after oral administration and found to vary considerably among… 
1977
1977
Photosensitization of the lens by 8-methoxypsoralen.
During the past decade, ambient ultraviolet radiation has been implicated in the age-related increase in fluorescence and… 
1972
1972
Isolation and identification of xanthotoxin (8-methoxypsoralen) and bergapten (5-methoxypsoralen) from celery infected with Sclerotinia sclerotiorum.
Methods for the production, isolation, and identification of xanthotoxin and bergapten from celery diseased by Sclerotinia… 
1961
1961
Hydroquinone Bleaching: Submitted for publication March 6, 1961. This study was approved by the Veterans Administration Hospital, Danville, Ill. From the Department of Dermatology, Northwestern…
Introduction Lightening pigmented blemishes with a bleaching agent has never been very satisfactory. This study was undertaken in…