Fenretinide

Known as: N-(4-Hydroxyphenyl)All-Trans Retinamide, 4-hydroxyphenylretinamide, N-(4-Hydroxyphenyl)-trans-Retinamide 
An orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide… (More)
National Institutes of Health

Papers overview

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2008
2008
Chronic and persistent lung infections cause the majority of morbidity and mortality in patients with cystic fibrosis (CF… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE The synthetic retinoid fenretinide administered for 5 years for prevention of second breast cancer showed no difference… (More)
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Highly Cited
2005
Highly Cited
2005
In obesity and type 2 diabetes, expression of the GLUT4 glucose transporter is decreased selectively in adipocytes. Adipose… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Because lung cancer is the leading cause of cancer-related death, new approaches for preventing and controlling the… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE Fenretinide (4HPR), a synthetic retinoid, induces apoptosis in neuroblastoma cells. A Phase I study in children with… (More)
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2002
2002
OBJECTIVE The aim of this study was to update the effect of fenretinide, a synthetic vitamin A analogue proposed for… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Fenretinide, a vitamin A analogue, has been shown to inhibit breast carcinogenesis in preclinical studies. We… (More)
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Review
1994
Review
1994
Chemoprevention drug development has the goal of identifying safe and effective chemopreventive agents for clinical use. Several… (More)
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Highly Cited
1993
Highly Cited
1993
PURPOSE Monitoring of fenretinide (4HPR) levels, kinetics, and effects on retinal was performed in patients who participated in a… (More)
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1989
1989
Fenretinide, N-(4-hydroxyphenyl)retinamide (HPR), is a synthetic retinoid which has been proven effective in inducing cell… (More)
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