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Vitamin A concentrations in liver determined by isotope dilution assay with tetradeuterated vitamin A and by biopsy in generally healthy adult humans.
TLDR
The vitamin A status in 11 generally healthy surgical patients was estimated by measuring the dilution of a 45-mg oral dose of tetradeuterated retinyl acetate and the total body reserves and liver concentrations of vitamin A were calculated.
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The enzymatic cleavage of beta-carotene into vitamin A by soluble enzymes of rat liver and intestine.
  • J. OlsonO. Hayaishi
  • Biology, Chemistry
    Proceedings of the National Academy of Sciences…
  • 1 November 1965
TLDR
In the present report an enzyme has been found in the supernatant solution of rat liver and intestine which converts 13-carotene into retinal and retinol as its sole products.
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Rapid, simultaneous determination of isomers of retinal, retinal oxime and retinol by high-performance liquid chromatography.
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Intestinal absorption, serum clearance, and interactions between lutein and beta-carotene when administered to human adults in separate or combined oral doses.
TLDR
Results show that carotenoids clearly interact with each other during intestinal absorption, metabolism, and serum clearance, although individual responses can differ markedly.
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The crystallization and characterization of L-glutamic acid dehydrogenase.
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Biological actions of carotenoids 1
TLDR
In epidemiological studies, the intake of carotenoid‐rich fruits and vegetables has been correlated with protection from some forms of cancer, particularly lung cancer, and serum β‐carotene levels have been associated with a decreased chance of developing lung cancer.
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Enzymatic formation of 9‐cis, 13‐cis, and all‐trans retinals from isomers of β‐carotene
  • A. NagaoJ. Olson
  • Biology, Chemistry
    FASEB journal : official publication of the…
  • 1 September 1994
TLDR
The oxidative conversion of 9‐cis β‐carotene to 9‐ cis and all‐trans retinals is the first identified enzymatic reaction for the formation of 9-cis retinal in animal tissues.
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Stoichiometric conversion of all trans-beta-carotene to retinal by pig intestinal extract.
TLDR
Preparations of pig intestinal mucosa clearly convert beta-carotene to retinal, in large part if not solely, by central cleavage, and whether eccentric cleavage plays a greater role in vivo than it does in vitro is still uncertain.
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Reversed-phase gradient high-performance liquid chromatographic procedure for simultaneous analysis of very polar to nonpolar retinoids, carotenoids and tocopherols in animal and plant samples.
  • A. BaruaJ. Olson
  • Chemistry
    Journal of chromatography. B, Biomedical sciences…
  • 10 April 1998
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Introduction: The colorful, fascinating world of the carotenoids: important physiologic modulators
  • J. OlsonN. Krinsky
  • Biology, Medicine
    FASEB journal : official publication of the…
  • 1 December 1995
TLDR
Chemists in the 19th century, foi'ebears of the biological scientists of today, pondei’ed both the nature and the purpose of these natural pigments, which have entered the authors' vocabulary.
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