FYN protein, human

Known as: p59-FYN, Src-Like Kinase, Proto-Oncogene Syn 
Tyrosine-protein kinase Fyn (537 aa, ~61 kDa) is encoded by the human FYN gene. This protein is involved in tyrosine phosphorylation, cytoskeleton… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Amyloid-beta (Aβ) oligomers are thought to trigger Alzheimer's disease pathophysiology. Cellular prion protein (PrPC) selectively… (More)
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Highly Cited
2012
Highly Cited
2012
Amid controversy, the cellular form of the prion protein PrP(c) has been proposed to mediate oligomeric amyloid-β (Aβ)-induced… (More)
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Highly Cited
2006
Highly Cited
2006
Group B coxsackieviruses (CVBs) must cross the epithelium as they initiate infection, but the mechanism by which this occurs… (More)
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Highly Cited
2004
Highly Cited
2004
The abnormal phosphorylation of tau protein on serines and threonines is a hallmark characteristic of the neurofibrillary tangles… (More)
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Highly Cited
2003
Highly Cited
2003
beta-Catenin has a key role in the formation of adherens junction through its interactions with E-cadherin and alpha-catenin. We… (More)
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Highly Cited
2001
Highly Cited
2001
The N-methyl-d-aspartate (NMDA) receptors play critical roles in synaptic plasticity, neuronal development, and excitotoxicity… (More)
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Highly Cited
2001
Highly Cited
2001
Using confocal laser scanning and double immunogold electron microscopy, we demonstrate that reggie-1 and -2 are colocalized in… (More)
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Highly Cited
1998
Highly Cited
1998
Caveolin-1 functions as a membrane adaptor to link the integrin alpha subunit to the tyrosine kinase Fyn. Upon integrin ligation… (More)
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Highly Cited
1994
Highly Cited
1994
MYELIN is the lipoprotein multimembrane that functions as an insulator preventing the flow of ion currents across the axonal… (More)
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Highly Cited
1994
Highly Cited
1994
Two src family kinases, lck and fyn, participate in the activation of T lymphocytes. Both of these protein tyrosine kinases are… (More)
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