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Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed exome sequencing and copy number… Expand In order to form a functional nervous system, neurones extend axons, often over long distances, to reach their targets. This… Expand Recognition molecules of the immunoglobulin superfamily have important roles in neuronal interactions during ontogeny, including… Expand Axons are guided along specific pathways by attractive and repulsive cues in the extracellular environment. Genetic and… Expand A Drosophila homolog of human Down syndrome cell adhesion molecule (DSCAM), an immunoglobulin superfamily member, was isolated by… Expand During development of the adult Drosophila visual system, axons of the eight photoreceptors in each ommatidium fasciculate… Expand Extending axons in the developing nervous system are guided in part by repulsive cues. Genetic analysis in Drosophila, reported… Expand The robo gene in Drosophila was identified in a large-scale mutant screen for genes that control the decision by axons to cross… Expand Neuronal growth cones navigate over long distances along specific pathways to find their correct targets. The mechanisms and… Expand The results of previous in vitro experiments indicate that a glycosylphosphatidylinositol (GPI)-anchored protein may play an… Expand