CXCL12 wt Allele

Known as: TLSF-B, TPAR1, SDF1A 
Human CXCL12 wild-type allele is located in the vicinity of 10q11.1 and is approximately 15 kb in length. This allele, which encodes stromal cell… (More)
National Institutes of Health

Related topics

Related topics

16 relations
10q11.1Acquired Immunodeficiency SyndromeAxon GuidanceCCR5 Signaling Pathway
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Broader (1)

CXCL12 gene

Papers overview

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Highly Cited
2015
Highly Cited
2015
The WHIM-like CXCR4S338X somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom’s Macroglobulinemia
CXCR4WHIM somatic mutations are common Waldenstrom’s Macroglobulinemia (WM), and are associated with clinical resistance to… (More)
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Review
2011
Review
2011
CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies?
Addition of multiple molecularly targeted agents to the existing armamentarium of chemotherapeutics and radiotherapies represents… (More)
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Highly Cited
2011
Highly Cited
2011
The IL-8-regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth.
The proinflammatory chemokine receptor CXCR7 that binds the ligands CXCL11 and CXCL12 (SDF-1a) is elevated in a variety of human… (More)
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Highly Cited
2006
Highly Cited
2006
Control of cell migration in the development of the posterior lateral line: antagonistic interactions between the chemokine receptors CXCR4 and CXCR7/RDC1
The formation of the posterior lateral line of teleosts depends on the migration of a primordium that originates near the otic… (More)
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Highly Cited
2005
Highly Cited
2005
Phenolic content of virgin olive oil improves ischemic reactive hyperemia in hypercholesterolemic patients.
OBJECTIVES The goal of this study was to evaluate the effects of the phenolic content of virgin olive oil on endothelial… (More)
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Highly Cited
2005
Highly Cited
2005
Transition from non-motile behaviour to directed migration during early PGC development in zebrafish.
The migration of zebrafish primordial germ cells (PGCs) is directed by SDF-1a and serves as a model for long-range chemokine… (More)
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2000
2000
Stromal cell-derived factor-1 a stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells : roles of phosphoinositide-3 kinase…
The stromal cell-derived factor-1 (SDF-1) is an alpha chemokine that binds to the CXCR4 receptor. Knock-out studies in mice… (More)
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1999
1999
The chemokine SDF-1α triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
The chemokine stromal cell-derived factor (SDF-1a), the ligand for the CXCR4 receptor, induces a wide variety of effects that… (More)
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Highly Cited
1998
Highly Cited
1998
The a-Chemokine , Stromal Cell-derived Factor-1 a , Binds to the Transmembrane G-protein-coupled CXCR4 Receptor and Activates Multiple Signal Transduction Pathways
The a-chemokine stromal cell-derived factor (SDF)-1a binds to the seven transmembrane G-protein-coupled CXCR-4 receptor and acts… (More)
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Highly Cited
1998
Highly Cited
1998
The alpha-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion.
CXCR4 is the receptor for the alpha-chemokine stromal cell-derived factor 1 (SDF-1) and has been shown to be expressed on a… (More)
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