Proto-Oncogene Proteins c-fyn

Known as: Proto Oncogene Protein c syn, c-fyn, Proto-Oncogene Proteins, Proto-Oncogene Protein c-syn 
Src-family kinases that associate with T-CELL ANTIGEN RECEPTOR and phosphorylate a wide variety of intracellular signaling molecules.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The accumulation of misfolded proteins is a fundamental pathogenic process in neurodegenerative diseases. However, the factors… (More)
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Highly Cited
2007
Highly Cited
2007
Src-specific activity has been reported to be elevated in a high percentage of colon cancer cell lines and tumors, but the… (More)
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Highly Cited
2005
Highly Cited
2005
Abnormal folding of alpha-synuclein (alpha-syn) is thought to lead to neurodegeneration and the characteristic symptoms of Lewy… (More)
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Highly Cited
2005
Highly Cited
2005
Multiple system atrophy (MSA) is a progressive, neurodegenerative disease characterized by parkinsonism, ataxia, autonomic… (More)
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Highly Cited
2003
Highly Cited
2003
We investigated the molecular and cellular actions of receptor protein tyrosine phosphatase (PTP) alpha in integrin signaling… (More)
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Highly Cited
2002
Highly Cited
2002
The purpose of this study is to examine the regulation of blood pressure and fluid and electrolyte homeostasis in mice… (More)
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1999
1999
We have investigated the interaction between Cbl and the Src-related tyrosine kinase Fyn. Fyn was observed to be constitutively… (More)
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Review
1998
Review
1998
Fyn is a 59 kDa member of the Src family of tyrosine kinases. The protein is synthesized and N-myristoylated on cytosolic… (More)
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Highly Cited
1995
Highly Cited
1995
MOUSE embryos lacking Csk, a negative regulator of Src family kinases, exhibit defects in neurulation and die at mid-gestation1,2… (More)
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Highly Cited
1987
Highly Cited
1987
It has been shown previously that deoxyguanosine residues in DNA are hydroxylated at the C-8 position both in vitro and in vivo… (More)
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