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Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system.
This invention relates to a flexible connector material of the type used in air circulating systems, such as air conditioning and warm air systems, to span the space between adjacent ducts, wherebyExpand
Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones.
Continuously cultured human neuroblastoma cell lines SK-N-SH, SK-N-BE(1), SK-N-BE(2), and SK-N-MC, as well
Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10.
Sox10 is a high-mobility-group transcriptional regulator in early neural crest. Without Sox10, no glia develop throughout the peripheral nervous system. Here we show that Sox10 is restricted in theExpand
Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration
Recognition molecules of the immunoglobulin superfamily have important roles in neuronal interactions during ontogeny, including migration, survival, axon guidance and synaptic targeting. TheirExpand
Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth
In spite of advances in understanding the role of the cellular prion protein (PrP) in neural cell interactions, the mechanisms of PrP function remain poorly characterized. We show that PrP interactsExpand
Disruption of the mouse L1 gene leads to malformations of the nervous system
The adhesion molecule L1 is a member of the immunoglobulin super-family1. L1 is involved in various recognition processes in the CMS and PNS2–3, and binding to L1 can activate signal transductionExpand
Analysis of the L1-Deficient Mouse Phenotype Reveals Cross-Talk between Sema3A and L1 Signaling Pathways in Axonal Guidance
In humans, defects of the corticospinal tract have been attributed to mutations in the gene encoding L1 CAM, a phenotype that is reproduced in L1-deficient mice. Using coculture assays, we reportExpand
Glycans and neural cell interactions
Carbohydrate-carrying molecules in the nervous system have important roles during development, regeneration and synaptic plasticity. Carbohydrates mediate interactions between recognition molecules,Expand
Axonal regrowth after spinal cord transection in adult zebrafish.
Using axonal tracers, we characterized the neurons projecting from the brain to the spinal cord as well as the terminal fields of ascending spinal projections in the brain of adult zebrafish withExpand
Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve
The cellular and subcellular localization of the neural cell adhesion molecules L1, N-CAM, and myelin-associated glycoprotein (MAG), their shared carbohydrate epitope L2/HNK-1, and the myelin basicExpand