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FCGR1A wt Allele

Known as: FCRI, FCGR1, FCG1 
Human FCGR1A wild-type allele is located within 1q21.2-q21.3 and is approximately 10 kb in length. This allele, which encodes high affinity… 
National Institutes of Health

Related topics

Related topics

5 relations
Antigen PresentationAntigen ProcessingLigand BindingReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1991
1991
Role of low-affinity Fc receptors in antibody-dependent tumor cell phagocytosis by human monocyte-derived macrophages.
Human monocyte-derived macrophages (MDM) mediate efficient antibody-dependent cellular cytotoxicity (ADCC) against a variety of… 
Highly Cited
1990
Highly Cited
1990
Characterization and isolation of a C-reactive protein receptor from the human monocytic cell line U-937.
Human C-reactive protein (CRP) is an acute phase reactant that is opsonic and an activator of macrophage tumoricidal function… 
Highly Cited
1990
Highly Cited
1990
Functional interactions of red cells sensitized by IgG1 and IgG3 human monoclonal anti-D with enzyme-modified human monocytes and FcR-bearing cell lines.
Highly Cited
1990
Highly Cited
1990
Human epidermal Langerhans cells express only the 40-kilodalton Fc gamma receptor (FcRII).
In man, three distinct classes of receptors for the Fc fragments of IgG (FcRI, II, III) have been defined. The FcRI has a Mr of… 
1990
1990
The Fc-receptor III of cultured human monocytes. Structural similarity with FcRIII of natural killer cells and role in the extracellular lysis of sensitized erythrocytes.
FcRIII is not present on peripheral blood monocytes, but becomes expressed upon culturing and can be demonstrated on tissue… 
1989
1989
Functional polymorphisms of Fc receptors in human monocyte-mediated cytotoxicity towards erythrocytes induced by murine isotype switch variants.
Human monocytes can be triggered to antibody-dependent cell-mediated cytotoxicity (ADCC) by murine antibodies. In this study, a… 
1989
1989
The Fc receptor, FcRI, and other activation molecules on human mononuclear phagocytes after treatment with interferon-gamma.
Human monocytes and the myeloid cell lines U937 and HL60 have been tested with monoclonal antibodies (MoAbs) reactive with 22… 
Highly Cited
1989
Highly Cited
1989
The FCγ receptor of natural killer cells is a phospholipid-linked membrane protein
THIS letter reported the isolation and partial characterization of a cDNA clone encoding a phospholipid-anchored form of CD16… 
1988
1988
Characterization of the human monocyte high affinity Fc receptor (hu FcRI).
1984
1984
Ligand inhibition studies on the role of Fc receptors in antibody-dependent cell-mediated cytotoxicity.
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