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FCGR1A wt Allele

Known as: FCRI, FCGR1, FCG1 
Human FCGR1A wild-type allele is located within 1q21.2-q21.3 and is approximately 10 kb in length. This allele, which encodes high affinity… 
National Institutes of Health

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Related topics

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Antigen PresentationAntigen ProcessingLigand BindingReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Congenic Mapping and Candidate Sequencing of Susceptibility Genes for Type 1 Diabetes in the NOD Mouse
Abstract: Inheritance of type 1 diabetes is polygenic with a major susceptibility gene located in the major histocompatibility… 
1991
1991
IgG Fc receptor heterogeneity in human peripheral nerves
ABSTRACT The presence of Fc‐receptors for IgG, FcRI (CD64), FcRII (CD32) and FcRIII (CD16) in human peripheral nerves was studied… 
Highly Cited
1990
Highly Cited
1990
Human epidermal Langerhans cells express only the 40-kilodalton Fc gamma receptor (FcRII).
In man, three distinct classes of receptors for the Fc fragments of IgG (FcRI, II, III) have been defined. The FcRI has a Mr of… 
1990
1990
The Fc-receptor III of cultured human monocytes. Structural similarity with FcRIII of natural killer cells and role in the extracellular lysis of sensitized erythrocytes.
FcRIII is not present on peripheral blood monocytes, but becomes expressed upon culturing and can be demonstrated on tissue… 
1989
1989
Functional polymorphisms of Fc receptors in human monocyte-mediated cytotoxicity towards erythrocytes induced by murine isotype switch variants.
Human monocytes can be triggered to antibody-dependent cell-mediated cytotoxicity (ADCC) by murine antibodies. In this study, a… 
Highly Cited
1989
Highly Cited
1989
The FCγ receptor of natural killer cells is a phospholipid-linked membrane protein
THIS letter reported the isolation and partial characterization of a cDNA clone encoding a phospholipid-anchored form of CD16… 
1989
1989
The Fc receptor, FcRI, and other activation molecules on human mononuclear phagocytes after treatment with interferon-gamma.
Human monocytes and the myeloid cell lines U937 and HL60 have been tested with monoclonal antibodies (MoAbs) reactive with 22… 
1988
1988
Characterization of the human monocyte high affinity Fc receptor (hu FcRI).
1984
1984
Ligand inhibition studies on the role of Fc receptors in antibody-dependent cell-mediated cytotoxicity.
1979
1979
The heterogeneity of Fc receptors on human peripheral mononuclear blood cells.
Fc-receptor positive peripheral blood mononuclear cells (PMBC) behaved differently after a temperature shift from 4 to 37 degrees… 
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