Enkephalins

Known as: Enkephalin, Enkephalins [Chemical/Ingredient] 
One of the three major families of endogenous opioid peptides. The enkephalins are pentapeptides that are widespread in the central and peripheral… (More)
National Institutes of Health

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Narrower (18)

BW 942CEK 209Enkephalin, LeucineFW 34569
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Broader (3)

Endogenous OpiatesEndorphinsNeurotransmitter Agents
In BloodNucleus Raphe MagnusOpioid ReceptorPeptides
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Papers overview

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Highly Cited
2002
Highly Cited
2002
Structure of Met-enkephalin in explicit aqueous solution using replica exchange molecular dynamics.
Replica exchange molecular dynamics (MD) simulations of Met-enkephalin in explicit solvent reveal helical and nonhelical… (More)
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Highly Cited
1992
Highly Cited
1992
A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes.
The mitogenic actions of epidermal growth factor (EGF) were examined in low-density, dissociated cultures of embryonic day 14… (More)
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Highly Cited
1990
Highly Cited
1990
D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons.
The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the… (More)
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Highly Cited
1986
Highly Cited
1986
Distribution of dynorphin and enkephalin peptides in the rat brain.
The neuroanatomical distribution of dynorphin B-like immunoreactivity (DYN-B) was studied in the adult male and female albino rat… (More)
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Highly Cited
1983
Highly Cited
1983
Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.
The conformationally restricted, cyclic, disulfide-containing, enkephalin analogs [2-D-penicillamine, 5-L-penicillamine… (More)
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Highly Cited
1979
Highly Cited
1979
Suggestive evidence for receptors for morphine and methionine-enkephalin on normal human blood T lymphocytes.
This study reports the in vitro influence of morphine, dextromoramide, levomoramide, and methionine-enkephalin upon normal human… (More)
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Highly Cited
1978
Highly Cited
1978
Immunohistochemical localization of enkephalin in rat brain and spinal cord.
The distribution of immunoreactive enkephalin in rat brain and spinal cord was studied by immunoperoxidase staining using… (More)
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Highly Cited
1977
Highly Cited
1977
ENKEPHALIN-LIKE IMMUNOREACTIVITY IN THE HUMAN GASTROINTESTINAL TRACT
Morphine has powerful actions on brain and gut. Peptides with opiate-like actions (endorphins, enkephalins) are known to be… (More)
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Highly Cited
1976
Highly Cited
1976
Immunohistochemical studies using antibodies to leucine-enkephalin: Initial observations on the nervous system of the rat
Enkephalins are peptides which have pharmacological properties similar to those of morphine. Guinea pigs were immunized with a… (More)
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Highly Cited
1975
Highly Cited
1975
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Enkephalin, a natural ligand for opiate receptors is composed of the pentapeptides H–Tyr–Gly–Gly–Phe–Met–OH and H–Tyr–Gly–Gly–Phe… (More)
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