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Enkephalins

Known as: Enkephalin, Enkephalins [Chemical/Ingredient] 
One of the three major families of endogenous opioid peptides. The enkephalins are pentapeptides that are widespread in the central and peripheral… Expand
National Institutes of Health

Related topics

Related topics

32 relations

Narrower (18)

BW 942CEK 209Enkephalin, LeucineFW 34569
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Broader (3)

Endogenous OpiatesEndorphinsNeurotransmitter Agents
In BloodNucleus Raphe MagnusOpioid ReceptorPeptides
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Endogenous and Exogenous Opioids in Pain.
Opioids are the most commonly used and effective analgesic treatments for severe pain, but they have recently come under scrutiny… Expand
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Highly Cited
2000
Highly Cited
2000
Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans.
Ghrelin, a novel GH-releasing acylated peptide, was recently isolated from rat stomach. It stimulated the release of GH from the… Expand
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Highly Cited
1999
Highly Cited
1999
Replica-exchange molecular dynamics method for protein folding
Abstract We have developed a formulation for molecular dynamics algorithm for the replica-exchange method. The effectiveness of… Expand
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Review
1998
Review
1998
Angiotensin, thirst, and sodium appetite.
Angiotensin (ANG) II is a powerful and phylogenetically widespread stimulus to thirst and sodium appetite. When it is injected… Expand
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Highly Cited
1994
Highly Cited
1994
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization.
Abstract A random primed expression cDNA library was constructed from the RNA of NG 108-15 cells. Pools of plasmid DNA were… Expand
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Highly Cited
1990
Highly Cited
1990
D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons.
The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the… Expand
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Highly Cited
1983
Highly Cited
1983
Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.
The conformationally restricted, cyclic, disulfide-containing, enkephalin analogs [2-D-penicillamine, 5-L-penicillamine… Expand
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Highly Cited
1978
Highly Cited
1978
Immunohistochemical localization of enkephalin in rat brain and spinal cord
The distribution of immunoreactive enkephalin in rat brain and spinal cord was studied by immunoperoxidase staining using… Expand
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Highly Cited
1977
Highly Cited
1977
Endogenous opioid peptides: multiple agonists and receptors
Opioid peptides were assayed by inhibition of 3H-naloxone and 3H-leu-enkephalin binding in brain homogenates and by depression of… Expand
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Highly Cited
1975
Highly Cited
1975
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Enkephalin, a natural ligand for opiate receptors is composed of the pentapeptides H–Tyr–Gly–Gly–Phe–Met–OH and H–Tyr–Gly–Gly–Phe… Expand
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