Endorphins

Known as: Endorphin, Endorphins [Chemical/Ingredient] 
One of the three major groups of endogenous opioid peptides. They are large peptides derived from the PRO-OPIOMELANOCORTIN precursor. The known… (More)

Topic mentions per year

Topic mentions per year

1976-2018
020040019762018

Papers overview

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Highly Cited
2001
Highly Cited
2001
Numerous studies have demonstrated that drugs of abuse activate the mesolimbic dopamine reward pathway, and it is widely held… (More)
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Highly Cited
1998
Highly Cited
1998
Opioid drugs play important roles in the clinical management of pain, as well as in the development and treatment of drug abuse… (More)
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Highly Cited
1996
Highly Cited
1996
A physiological role for beta-endorphin in endogenous pain inhibition was investigated by targeted mutagenesis of the… (More)
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Highly Cited
1994
Highly Cited
1994
POMC, the precursor of ACTH, MSH, and beta-endorphin peptides, is expressed in the pituitary and in two sites in the brain, in… (More)
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Highly Cited
1989
Highly Cited
1989
Social relationships are integral to the behaviour of many mammalian species. Primates are unusual in that their social… (More)
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Highly Cited
1983
Highly Cited
1983
The distribution of corticotropin-releasing factor (CRF)-immunoreactive cells and fibers has been examined in the brains of… (More)
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Highly Cited
1978
Highly Cited
1978
The effect of naloxone on dental postoperative pain was studied to examine the hypothesis that endorphins mediate placebo… (More)
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Highly Cited
1977
Highly Cited
1977
Double-antibody immunoprecipitation procedures with antisera to endorphins and to corticotropin (ACTH) were used to study the… (More)
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Highly Cited
1977
Highly Cited
1977
The opiate-like peptide beta-endorphin and adrenocorticotropin are concomitantly secreted in increased amounts by the… (More)
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