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ERCC3 wt Allele

Known as: Excision-Repair, Complementing Defective, In Chinese Hamster, 3 Gene, Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 (Xeroderma Pigmentosum Group B Complementing) Gene, Basic Transcription Factor 2 89 kDa Subunit Gene 
Human ERCC3 wild-type allele is located within 2q21 and is approximately 37 kb in length. This allele, which encodes TFIIH basal transcription factor… 
National Institutes of Health

Related topics

Related topics

13 relations
2q21Chromatin Remodeling Complex and Coactivator PathwayDNA RepairEstrogen Receptor Regulation by CARM1 Pathway

Broader (1)

ERCC3 gene

Papers overview

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Highly Cited
2007
Highly Cited
2007
Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH
Mutations in the XPD subunit of the DNA repair/transcription factor TFIIH yield the rare genetic disorder trichothiodystrophy… 
Highly Cited
2001
Highly Cited
2001
A temperature-sensitive disorder in basal transcription and DNA repair in humans
The xeroderma pigmentosum group D (XPD) helicase subunit of TFIIH functions in DNA repair and transcription initiation. Different… 
Highly Cited
1999
Highly Cited
1999
Activation of Transcription in Vitro by the BRCA1 Carboxyl-terminal Domain*
The breast and ovarian specific tumor suppressor protein, BRCA1, has been shown to be a transcription factor because its carboxyl… 
1999
1999
Transcription Factor TFIIH Is Required for Promoter Melting In Vivo
ABSTRACT The Rad25 protein in yeast is a DNA helicase and a subunit of the general transcription factor TFIIH. While in vitro… 
1998
1998
TATA Binding Protein Discriminates between Different Lesions on DNA, Resulting in a Transcription Decrease
ABSTRACT DNA damage recognition by basal transcription factors follows different mechanisms. Using transcription-competition… 
Review
1998
Review
1998
Dual functions of DNA repair genes: molecular, cellular, and clinical implications
The complex series of DNA repair pathways that are used to repair damage to cellular DNA employ many different proteins. A… 
Review
1997
Review
1997
Multi-site phosphorylation of p53 by protein kinases inducible by p53 and DNA damage.
Introduction The p53 tumour suppressor protein is a key element in the cell’s defence against tumour development, and as such is… 
Highly Cited
1996
Highly Cited
1996
Reconstitution of TFIIH and Requirement of Its DNA Helicase Subunits, Rad3 and Rad25, in the Incision Step of Nucleotide Excision Repair (*)
Yeast TFIIH is composed of six subunits: Rad3, Rad25, TFB1, SSL1, p55, and p38. In addition to TFIIH, we have purified a… 
Review
1995
Review
1995
TFIIH: a link between transcription, DNA repair and cell cycle regulation.
Highly Cited
1994
Highly Cited
1994
Deficient repair of cisplatin-DNA adducts identified in human testicular teratoma cell lines established from tumours from untreated patients.
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